Ambrisentan • ChemWhat中文网 | 凯望化学与生物数据库

Ambrisentan Impurity 6 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 6 is chemically Methyl 2,3-dihydroxy-3,3-diphenylpropanoate. Ambrisentan Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Rac O-Demethyl Ambrisentan CAS#: 1106685-85-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Rac O-Demethyl Ambrisentan is chemically 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic acid. Rac O-Demethyl Ambrisentan is supplied with detailed characterization data compliant with regulatory guideline. Rac O-Demethyl Ambrisentan can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Impurity 4 CAS#: 14001-64-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 4 is chemically 4,6-Dimethyl-2-(methylthio)pyrimidine. Ambrisentan Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Impurity 5 CAS#: 1106685-94-2

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 5 is chemically (S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic acid. Ambrisentan Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Impurity 3 CAS#: 98484-90-3

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 3 is chemically 4,6-Dimethyl-5,6-dihydropyrimidine-2(1H)-thione. Ambrisentan Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Impurity 2 CAS#: 947-91-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 2 is chemically 2,2-Diphenyl acetaldehyde . Ambrisentan Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Impurity 1 CAS#: 178306-51-9

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Impurity 1 is chemically 2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid. Ambrisentan Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan Epoxide CAS#: 76527-25-8

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan Epoxide is chemically Methyl 3,3-diphenyloxirane-2-carboxylate. Ambrisentan Epoxide is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan Epoxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambrisentan D10 CAS#: 1046116-27-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambrisentan D10 is chemically (S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-bis(phenyl-d5)propanoic acid. Ambrisentan D10 is supplied with detailed characterization data compliant with regulatory guideline. Ambrisentan D10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Rac-Ambrisentan D3 CAS#: 1189479-60-4

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Rac-Ambrisentan D3 is chemically 2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-(methoxy-d3)-3,3-diphenylpropanoic acid. Rac-Ambrisentan D3 is supplied with detailed characterization data compliant with regulatory guideline. Rac-Ambrisentan D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambrisentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Ambrisentan Impurity 6
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl 2,3-dihydroxy-3,3-diphenylpropanoate
分子式	C16H16O4
分子量	272.3
InChI
InChI Key
Canonical SMILES	OC(C(C(OC)=O)O)(C1=CC=CC=C1)C2=CC=CC=C2

英文名	Rac O-Demethyl Ambrisentan
分子结构
CAS编号	1106685-85-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic acid
分子式	C21H20N2O4
分子量	364.4
InChI
InChI Key
Canonical SMILES	OC(C1=CC=CC=C1)(C2=CC=CC=C2)C(C(O)=O)OC3=NC(C)=CC(C)=N3

英文名	Ambrisentan Impurity 4
分子结构
CAS编号	14001-64-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	4,6-Dimethyl-2-(methylthio)pyrimidine
分子式	C7H10N2S
分子量	154.2
InChI
InChI Key
Canonical SMILES	CSC1=NC(C)=CC(C)=N1

英文名	Ambrisentan Impurity 5
分子结构
CAS编号	1106685-94-2
EINECS Number
MDL Number
Beilstein Registry Number
别名	(S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-hydroxy-3,3-diphenylpropanoic acid
分子式	C21H20N2O4
分子量	364.4
InChI
InChI Key
Canonical SMILES	OC(C1=CC=CC=C1)(C2=CC=CC=C2)[C@@H](C(O)=O)OC3=NC(C)=CC(C)=N3

英文名	Ambrisentan Impurity 3
分子结构
CAS编号	98484-90-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	4,6-Dimethyl-5,6-dihydropyrimidine-2(1H)-thione
分子式	C6H10N2S
分子量	142.2
InChI
InChI Key
Canonical SMILES	S=C1N=C(C)CC(C)N1

英文名	Ambrisentan Impurity 2
分子结构
CAS编号	947-91-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2,2-Diphenyl acetaldehyde
分子式	C14H12O
分子量	196.2
InChI
InChI Key
Canonical SMILES	O=CC(C1=CC=CC=C1)C2=CC=CC=C2

英文名	Ambrisentan Impurity 1
分子结构
CAS编号	178306-51-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Hydroxy-3-methoxy-3,3-diphenylpropanoic acid
分子式	C16H16O4
分子量	272.3
InChI
InChI Key
Canonical SMILES	OC(C(O)=O)C(C1=CC=CC=C1)(C2=CC=CC=C2)OC

英文名	Ambrisentan Epoxide
分子结构
CAS编号	76527-25-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl 3,3-diphenyloxirane-2-carboxylate
分子式	C16H14O3
分子量	254.3
InChI
InChI Key
Canonical SMILES	O=C(C1C(C2=CC=CC=C2)(C3=CC=CC=C3)O1)OC

英文名	Ambrisentan D10
分子结构
CAS编号	1046116-27-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	(S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-bis(phenyl-d5)propanoic acid
分子式	C22H12D10N2O4
分子量	388.5
InChI
InChI Key
Canonical SMILES	COC(C(C([2H])=C1[2H])=C(C([2H])=C1[2H])[2H])(C(C([2H])=C2[2H])=C(C([2H])=C2[2H])[2H])[C@@H](C(O)=O)OC3=NC(C)=CC(C)=N3

英文名	Rac-Ambrisentan D3
分子结构
CAS编号	1189479-60-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-(methoxy-d3)-3,3-diphenylpropanoic acid
分子式	C22H19D3N2O4
分子量	381.5
InChI
InChI Key
Canonical SMILES	OC(C(OC1=NC(C)=CC(C)=N1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OC([2H])([2H])[2H])=O