Ambroxol • ChemWhat中文网 | 凯望化学与生物数据库

Ambroxol CAS#: 18683-91-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	23828-92-4 (HCl salt)

Use Pattern

Ambroxol is chemically Trans-4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol (as per EP). Ambroxol is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 7 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 7 is chemically (S)-N-(2,4-Dibromo-6-((((1r,4S)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxypropanamide hydrochloride. Ambroxol Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 8 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 8 is chemically N-(2,4-Dibromo-6-((((1r,4r)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxyacetamide. Ambroxol Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 9 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 9 is chemically N-(2,4-Dibromo-6-((((1r,4r)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxypropanamide. Ambroxol Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 6 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 6 is chemically 2-(((4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexyl)oxy)methyl)-4-(2-(tert-butylamino)-1-hydroxyethyl)phenol. Ambroxol Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 5 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 5 is chemically (1r,4r)-4-((2-amino-3-bromobenzyl)amino)cyclohexan-1-ol hydrochloride. Ambroxol Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso-Ambroxol CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso-Ambroxol is chemically N-(2-Amino-3,5-dibromobenzyl)-N-((1r,4r)-4-hydroxycyclohexyl)nitrous amide. N-Nitroso-Ambroxol is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso-Ambroxol can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol D5 CAS#: 1246818-80-3

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol D5 is chemically (1r,4r)-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexan-1,2,2,6,6-d5-1-ol. Ambroxol D5 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Impurity 4 CAS#: 1332582-28-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Impurity 4 is chemically 4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexan-1-ol. Ambroxol Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Ambroxol Cycloimine Impurity CAS#: 2088879-81-4

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Ambroxol Cycloimine Impurity is chemically (1r,4r)-4-(6,8-Dibromoquinazolin-3(4H)-yl)cyclohexan-1-ol. Ambroxol Cycloimine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Ambroxol Cycloimine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Ambroxol . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Ambroxol
分子结构
CAS编号	18683-91-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	Trans-4-[(2-Amino-3,5-dibromobenzyl)amino]cyclohexanol (as per EP)
分子式	C13H18Br2N2O
分子量	378.1
InChI
InChI Key
Canonical SMILES	NC1=C(Br)C=C(Br)C=C1CN[C@H]2CC[C@H](O)CC2

英文名	Ambroxol Impurity 7
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(S)-N-(2,4-Dibromo-6-((((1r,4S)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxypropanamide hydrochloride
分子式	C16H22Br2N2O3 : HCl
分子量	450.2 : 36.5
InChI
InChI Key
Canonical SMILES	BrC1=CC(Br)=C(NC([C@H](C)O)=O)C(CN[C@H]2CC[C@H](O)CC2)=C1.Cl

英文名	Ambroxol Impurity 8
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(2,4-Dibromo-6-((((1r,4r)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxyacetamide
分子式	C15H20Br2N2O3
分子量	436.1
InChI
InChI Key
Canonical SMILES	O[C@@H]1CC[C@@H](NCC2=CC(Br)=CC(Br)=C2NC(C(O)[H])=O)CC1

英文名	Ambroxol Impurity 9
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(2,4-Dibromo-6-((((1r,4r)-4-hydroxycyclohexyl)amino)methyl)phenyl)-2-hydroxypropanamide
分子式	C16H22Br2N2O3
分子量	450.2
InChI
InChI Key
Canonical SMILES	O[C@@H]1CC[C@@H](NCC2=CC(Br)=CC(Br)=C2NC(C(C)O)=O)CC1

英文名	Ambroxol Impurity 6
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(((4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexyl)oxy)methyl)-4-(2-(tert-butylamino)-1-hydroxyethyl)phenol
分子式	C26H37Br2N3O3
分子量	599.4
InChI
InChI Key
Canonical SMILES	BrC1=C(N)C(CNC2CCC(OCC3=C(O)C=CC(C(O)CNC(C)(C)C)=C3)CC2)=CC(Br)=C1

英文名	Ambroxol Impurity 5
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(1r,4r)-4-((2-amino-3-bromobenzyl)amino)cyclohexan-1-ol hydrochloride
分子式	C13H19BrN2O : HCl
分子量	299.2 : 36.5
InChI
InChI Key
Canonical SMILES	NC1=C(Br)C=CC=C1CN[C@@H]2CC[C@@H](O)CC2.Cl

英文名	N-Nitroso-Ambroxol
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(2-Amino-3,5-dibromobenzyl)-N-((1r,4r)-4-hydroxycyclohexyl)nitrous amide
分子式	C13H17Br2N3O2
分子量	407.1
InChI
InChI Key
Canonical SMILES	O[C@H]1CC[C@H](N(N=O)CC2=C(N)C(Br)=CC(Br)=C2)CC1

英文名	Ambroxol D5
分子结构
CAS编号	1246818-80-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	(1r,4r)-4-((2-Amino-3,5-dibromobenzyl)amino)cyclohexan-1,2,2,6,6-d5-1-ol
分子式	C13H13D5Br2N2O
分子量	383.1
InChI
InChI Key
Canonical SMILES	NC1=C(C=C(Br)C=C1Br)CN[C@H]2CC([2H])([2H])[C@@](O)([2H])C([2H])([2H])C2

英文名	Ambroxol Impurity 4
分子结构
CAS编号	1332582-28-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(6,8-Dibromo-1,4-dihydroquinazolin-3(2H)-yl)cyclohexan-1-ol
分子式	C14H18Br2N2O
分子量	390.1
InChI
InChI Key
Canonical SMILES	OC1CCC(N2CNC3=C(C=C(Br)C=C3Br)C2)CC1

英文名	Ambroxol Cycloimine Impurity
分子结构
CAS编号	2088879-81-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	(1r,4r)-4-(6,8-Dibromoquinazolin-3(4H)-yl)cyclohexan-1-ol
分子式	C14H16Br2N2O
分子量	388.1
InChI
InChI Key
Canonical SMILES	BrC1=CC(Br)=C(N=CN([C@H]2CC[C@H](O)CC2)C3)C3=C1