Aprepitant Impurity 14 CAS#: 638990-20-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Impurity 14
分子结构
CAS编号 638990-20-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 2,2′-Oxybis(4-benzylmorpholin-3-one)
分子式 C22H24N2O5
分子量 396.4
InChI
InChI Key
Canonical SMILES O=C1N(CCOC1OC2OCCN(CC3=CC=CC=C3)C2=O)CC4=CC=CC=C4

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Impurity 14 is chemically 2,2′-Oxybis(4-benzylmorpholin-3-one). Aprepitant Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Impurity 8 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Impurity 8
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(3-fluorophenyl)morpholine hydrochloride
分子式 C20H18F7NO2 : HCl
分子量 437.4 : 36.5
InChI
InChI Key
Canonical SMILES FC1=CC([C@@H]2NCCO[C@@H]2O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)=CC=C1.Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 172678-47-6 (free base)
Use Pattern
Aprepitant Impurity 8 is chemically (2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(3-fluorophenyl)morpholine hydrochloride. Aprepitant Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Impurity 5 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Impurity 5
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 5-(((2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4′-fluoro-[1,1′-biphenyl]-3-yl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
分子式 C29H25F7N4O3
分子量 610.5
InChI
InChI Key
Canonical SMILES O=C1NNC(CN2[C@H](C3=CC(C4=CC=C(F)C=C4)=CC=C3)[C@@H](O[C@H](C)C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)OCC2)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Impurity 5 is chemically 5-(((2R,3R)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4′-fluoro-[1,1′-biphenyl]-3-yl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one. Aprepitant Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Nitroso Impurity 3 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Nitroso Impurity 3
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
分子式 C20H17F7N2O3
分子量 466.4
InChI
InChI Key
Canonical SMILES C[C@@H](C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)O[C@H]2OCCN(N=O)[C@H]2C3=CC=C(F)C=C3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Nitroso Impurity 3 is chemically (2R,3S)-2-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine. Aprepitant Nitroso Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Nitroso Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Nitroso Impurity 5 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Nitroso Impurity 5
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
分子式 C20H17F7N2O3
分子量 466.4
InChI
InChI Key
Canonical SMILES O=NN1[C@H](C2=CC=C(F)C=C2)[C@@H](O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)OCC1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Nitroso Impurity 5 is chemically (2R,3R)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine. Aprepitant Nitroso Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Nitroso Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Nitroso Impurity 1 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Nitroso Impurity 1
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
分子式 C20H17F7N2O3
分子量 466.4
InChI
InChI Key
Canonical SMILES O=NN1[C@@H](C2=CC=C(F)C=C2)[C@@H](O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)OCC1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Nitroso Impurity 1 is chemically (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine. Aprepitant Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Impurity 12 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Impurity 12
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 Methyl 2-(2-amino-2-oxoethyl)-1-methylhydrazine-1-carboxylate
分子式 C5H11N3O3
分子量 161.2
InChI
InChI Key
Canonical SMILES O=C(N(C)NCC(N)=O)OC

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Impurity 12 is chemically Methyl 2-(2-amino-2-oxoethyl)-1-methylhydrazine-1-carboxylate. Aprepitant Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Impurity 9 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Impurity 9
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-5-(((1-(4-fluorophenyl)-2-hydroxyethyl)amino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
分子式 C11H13FN4O2
分子量 252.2
InChI
InChI Key
Canonical SMILES O=C1NNC(CN[C@H](C2=CC=C(F)C=C2)CO)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Impurity 9 is chemically (R)-5-(((1-(4-fluorophenyl)-2-hydroxyethyl)amino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one. Aprepitant Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Nitroso Impurity 6 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Nitroso Impurity 6
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine
分子式 C20H17F7N2O3
分子量 466.4
InChI
InChI Key
Canonical SMILES O=NN1[C@@H](C2=CC=C(F)C=C2)[C@H](O[C@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)OCC1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Nitroso Impurity 6 is chemically (2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-nitrosomorpholine. Aprepitant Nitroso Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Nitroso Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Aprepitant Nitroso Impurity 7 CAS#: 1185503-26-7

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Aprepitant Nitroso Impurity 7
分子结构
CAS编号 1185503-26-7
EINECS Number
MDL Number
Beilstein Registry Number
别名 Methyl (Z)-2-(1-amino-2-chloroethylidene)hydrazine-1-carboxylate
分子式 C4H8ClN3O2
分子量 165.6
InChI
InChI Key
Canonical SMILES N/C(CCl)=NNC(OC)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Aprepitant Nitroso Impurity 7 is chemically Methyl (Z)-2-(1-amino-2-chloroethylidene)hydrazine-1-carboxylate. Aprepitant Nitroso Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Aprepitant Nitroso Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Aprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.