Artesunate • ChemWhat中文网 | 凯望化学与生物数据库

9-Desmethylene 9-Oxo-Artemisitene CAS#: 150930-12-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

9-Desmethylene 9-Oxo-Artemisitene is chemically (3R,5aS,6R,8aR,12S,12aR)-3,6-Dimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,10-dione. 9-Desmethylene 9-Oxo-Artemisitene is supplied with detailed characterization data compliant with regulatory guideline. 9-Desmethylene 9-Oxo-Artemisitene can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Impurity 2 CAS#: 1812179-50-2

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate Impurity 2 is chemically (3S,4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde. Artesunate Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Artesunate Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Impurity 3 CAS#: 149588-86-3

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate Impurity 3 is chemically (3R,4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde. Artesunate Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Artesunate Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Impurity 1 CAS#: 2418566-38-6

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate Impurity 1 is chemically 1,4,7-Trimethyl-6a,7,8,9-tetrahydro-6H-pyrrolo[3,2,1-ij]quinolin-2(31H)-one. Artesunate Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Artesunate Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Peroxy Hemiacetal CAS#: 958447-25-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate Peroxy Hemiacetal is chemically (4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde. It is also known as Peroxy Hemiacetal , Re-arranged peroxide. Artesunate Peroxy Hemiacetal is supplied with detailed characterization data compliant with regulatory guideline. Artesunate Peroxy Hemiacetal can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Related Compound D CAS#: 93787-88-3

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate Related Compound D is chemically Methyl ((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl) succinate. Artesunate Related Compound D is supplied with detailed characterization data compliant with regulatory guideline. Artesunate Related Compound D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate-D3 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate-D3 is chemically 4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6-Dimethyl-9-(methyl-d3)decahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)-4-oxobutanoic acid. Artesunate-D3 is supplied with detailed characterization data compliant with regulatory guideline. Artesunate-D3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate-D4 CAS#: 1316753-15-7

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Artesunate-D4 is chemically 4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic-2,2,3,3-d4 acid. Artesunate-D4 is supplied with detailed characterization data compliant with regulatory guideline. Artesunate-D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate CAS#: 88495-63-0

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	82864-68-4 (Na salt) ; 911206-46-7 (K salt)

Use Pattern

Artesunate is chemically Butanedioic acid mono[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester. Artesunate is supplied with detailed characterization data compliant with regulatory guideline. Artesunate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Artesunate . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Artesunate Impurity C CAS#: 82596-30-3

By great_watson-int, 7th September 2023

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance
Solubility
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

Use Pattern

Artesunate Impurity C is an impurity of API Artesunate.

英文名	9-Desmethylene 9-Oxo-Artemisitene
分子结构
CAS编号	150930-12-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	(3R,5aS,6R,8aR,12S,12aR)-3,6-Dimethyloctahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene-9,10-dione
分子式	C14H18O6
分子量	282.3
InChI
InChI Key
Canonical SMILES	O=C1[C@@](CC[C@H]2C)([H])[C@@]([C@@]2([H])CC3)(OO4)[C@@](OC1=O)([H])O[C@@]34C

英文名	Artesunate Impurity 2
分子结构
CAS编号	1812179-50-2
EINECS Number
MDL Number
Beilstein Registry Number
别名	(3S,4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde
分子式	C15H24O5
分子量	284.4
InChI
InChI Key
Canonical SMILES	CC(CC[C@H]1[C@H](C)CC[C@]2([H])[C@]1(C=O)OO[C@H](O)[C@@H]2C)=O

英文名	Artesunate Impurity 3
分子结构
CAS编号	149588-86-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	(3R,4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde
分子式	C15H24O5
分子量	284.4
InChI
InChI Key
Canonical SMILES	CC(CC[C@H]1[C@H](C)CC[C@]2([H])[C@]1(C=O)OO[C@@H](O)[C@@H]2C)=O

英文名	Artesunate Impurity 1
分子结构
CAS编号	2418566-38-6
EINECS Number
MDL Number
Beilstein Registry Number
别名	1,4,7-Trimethyl-6a,7,8,9-tetrahydro-6H-pyrrolo[3,2,1-ij]quinolin-2(31H)-one
分子式	C14H19NO
分子量	217.3
InChI
InChI Key
Canonical SMILES	O=C1N2C(C)=CCC3C2C(CCC3C)=C1C

英文名	Artesunate Peroxy Hemiacetal
分子结构
CAS编号	958447-25-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	(4R,4aS,7R,8S,8aR)-3-hydroxy-4,7-dimethyl-8-(3-oxobutyl)hexahydrobenzo[c][1,2]dioxine-8a(3H)-carbaldehyde
分子式	C15H24O5
分子量	284.4
InChI
InChI Key
Canonical SMILES	CC(CC[C@@]1([H])[C@H](C)CC[C@]2([H])[C@]1(C([H])=O)OOC(O)[C@@H]2C)=O

英文名	Artesunate Related Compound D
分子结构
CAS编号	93787-88-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl ((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl) succinate
分子式	C20H30O8
分子量	398.5
InChI
InChI Key
Canonical SMILES	[H][C@@]1(CC[C@@](C)(OO2)O3)[C@]2([C@]3([H])O[C@@H](OC(CCC(OC)=O)=O)[C@@H]4C)[C@@]4([H])CC[C@H]1C

英文名	Artesunate-D3
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6-Dimethyl-9-(methyl-d3)decahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)-4-oxobutanoic acid
分子式	C19H25D3O8
分子量	387.4
InChI
InChI Key
Canonical SMILES	OC(CCC(O[C@@H]1O[C@@]2([H])[C@@]34[C@](CC[C@@](C)(OO4)O2)([H])[C@H](C)CC[C@@]3([H])[C@H]1C([2H])([2H])[2H])=O)=O

英文名	Artesunate-D4
分子结构
CAS编号	1316753-15-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-Oxo-4-(((3R,5aS,6R,8aS,9R,10S,12R,12aR)-3,6,9-trimethyldecahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromen-10-yl)oxy)butanoic-2,2,3,3-d4 acid
分子式	C19H24D4O8
分子量	388.5
InChI
InChI Key
Canonical SMILES	OC(C([2H])([2H])C([2H])([2H])C(O[C@@H]1O[C@@]2([H])[C@@]34[C@](CC[C@@](C)(OO4)O2)([H])[C@H](C)CC[C@@]3([H])[C@H]1C)=O)=O

英文名	Artesunate
分子结构
CAS编号	88495-63-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	Butanedioic acid mono[(3R,5aS,6R,8aS,9R,10R,12R,12aR)-decahydro-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j]-1,2-benzodioxepin-10-yl] ester
分子式	C19H28O8
分子量	384.4
InChI
InChI Key
Canonical SMILES	OC(CCC(O[C@@H]1O[C@@]2([H])[C@@]34[C@](CC[C@@](C)(OO4)O2)([H])[C@H](C)CC[C@@]3([H])[C@H]1C)=O)=O

英文名	Artesunate Impurity C
分子结构
CAS编号	82596-30-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	(3R,5aS,6R,8aS,12R,12aR)-3,6,9-Trimethyl-3,4,5,5a,6,7,8,8a-octahydro-12H-3,12-epoxy[1,2]dioxepino[4,3-i]isochromene
分子式	C15H22O4
分子量	266.34
InChI
InChI Key
Canonical SMILES