Axitinib • ChemWhat中文网 | 凯望化学与生物数据库

Axitinib Nitroso Impurity 4 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 4 is chemically 2-((3-Iodo-1-nitroso-1H-indazol-6-yl)thio)-N-methylbenzamide. Axitinib Nitroso Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Nitroso Impurity 3 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 3 is chemically N-Methyl-2-((1-nitroso-1H-indazol-6-yl)thio)benzamide. Axitinib Nitroso Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 16 CAS#: 886230-75-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 16 is chemically (E)-6-Nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole. Axitinib Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 25 CAS#: 147-93-3

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 25 is chemically 2-Mercaptobenzoic acid. Axitinib Impurity 25 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 25 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Nitroso Impurity 2 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Nitroso Impurity 2 is chemically 6-Iodo-1-nitroso-1H-indazole. Axitinib Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 26 CAS#: 885126-34-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 26 is chemically 2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide. Axitinib Impurity 26 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 26 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib-d3 CAS#: 1126623-89-9

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib-d3 is chemically (E)-N-(Methyl-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. Axitinib-d3 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib-d3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 24 CAS#: 1862-88-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 24 is chemically 2-Hydroxy-N-methylbenzamide. Axitinib Impurity 24 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 24 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Axitinib CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Axitinib is chemically (E)-N-methyl-2-((1-nitroso-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide. N-Nitroso Axitinib is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Axitinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Axitinib Impurity 19 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Axitinib Impurity 19 is chemically 5-iodo-3-(2-(pyridin-2-yl)ethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole . Axitinib Impurity 19 is supplied with detailed characterization data compliant with regulatory guideline. Axitinib Impurity 19 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Axitinib . The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Axitinib Nitroso Impurity 4
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-((3-Iodo-1-nitroso-1H-indazol-6-yl)thio)-N-methylbenzamide
分子式	C15H11IN4O2S
分子量	438.2
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=CC=CC=C1SC2=CC3=C(C=C2)C(I)=NN3N=O

英文名	Axitinib Nitroso Impurity 3
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-Methyl-2-((1-nitroso-1H-indazol-6-yl)thio)benzamide
分子式	C15H12N4O2S
分子量	312.3
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=CC=CC=C1SC2=CC3=C(C=C2)C=NN3N=O

英文名	Axitinib Impurity 16
分子结构
CAS编号	886230-75-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	(E)-6-Nitro-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
分子式	C19H18N4O3
分子量	350.4
InChI
InChI Key
Canonical SMILES	O=[N+](C1=CC2=C(C=C1)C(/C=C/C3=NC=CC=C3)=NN2C4CCCCO4)[O-]

英文名	Axitinib Impurity 25
分子结构
CAS编号	147-93-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Mercaptobenzoic acid
分子式	C7H6O2S
分子量	154.2
InChI
InChI Key
Canonical SMILES	OC(C(C=CC=C1)=C1S)=O

英文名	Axitinib Nitroso Impurity 2
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	6-Iodo-1-nitroso-1H-indazole
分子式	C7H4IN3O
分子量	273.0
InChI
InChI Key
Canonical SMILES	O=NN1N=CC2=C1C=C(I)C=C2

英文名	Axitinib Impurity 26
分子结构
CAS编号	885126-34-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-((3-Iodo-1H-indazol-6-yl)thio)-N-methylbenzamide
分子式	C15H12IN3OS
分子量	409.2
InChI
InChI Key
Canonical SMILES	IC1=NNC2=CC(SC(C=CC=C3)=C3C(NC)=O)=CC=C21

英文名	Axitinib-d3
分子结构
CAS编号	1126623-89-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	(E)-N-(Methyl-d3)-2-((3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
分子式	C22H15D3N4OS
分子量	389.5
InChI
InChI Key
Canonical SMILES	O=C(NC([2H])([2H])[2H])C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NNC3=C2

英文名	Axitinib Impurity 24
分子结构
CAS编号	1862-88-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Hydroxy-N-methylbenzamide
分子式	C8H9NO2
分子量	151.2
InChI
InChI Key
Canonical SMILES	O=C(C(C=CC=C1)=C1O)NC

英文名	N-Nitroso Axitinib
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(E)-N-methyl-2-((1-nitroso-3-(2-(pyridin-2-yl)vinyl)-1H-indazol-6-yl)thio)benzamide
分子式	C22H17N5O2S
分子量	415.5
InChI
InChI Key
Canonical SMILES	O=C(NC)C1=C(C=CC=C1)SC2=CC=C3C(/C=C/C4=CC=CC=N4)=NN(N=O)C3=C2

英文名	Axitinib Impurity 19
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-iodo-3-(2-(pyridin-2-yl)ethyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole
分子式	C19H20IN3O
分子量	433.3
InChI
InChI Key
Canonical SMILES	IC1=CC2=C(N(C3CCCCO3)N=C2CCC4=NC=CC=C4)C=C1