Cladribine • ChemWhat中文网 | 凯望化学与生物数据库

Cladribine Impurity 3 CAS#: 244097-87-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 3 is chemically (2S,3R,5S)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Cladribine Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Monophosphate CAS#: 104959-31-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	104959-32-2 (free base) ; 104959-33-3 (Disodium salt) ; 104959-36-6 (Ca salt)

Use Pattern

Cladribine Monophosphate is chemically Sodium ((2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate. Cladribine Monophosphate is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Monophosphate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Impurity 6 CAS#: 136834-39-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 6 is chemically 2-Chloro-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol. Cladribine Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Impurity 4 CAS#: 106867-30-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 4 is chemically ((2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate. Cladribine Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine 13C5 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine 13C5 is chemically (2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl-13C)tetrahydrofuran-3-ol-2,3,4,5-13C4. Cladribine 13C5 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine 13C5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Impurity 5 CAS#: 13368-14-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 5 is chemically 2-Chloro-7H-purin-6-ol. Cladribine Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Mono Benzoate Impurity CAS#: 152463-98-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Mono Benzoate Impurity is chemically (2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetra hydrofuran-3-yl-4-methyl benzoate. Cladribine Mono Benzoate Impurity is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Mono Benzoate Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Impurity 1 CAS#: 172792-37-9

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 1 is chemically (2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Cladribine Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine Impurity 2 CAS#: 3413-66-9

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine Impurity 2 is chemically (2R,3S,5S)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Cladribine Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Cladribine Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Cladribine CAS#: 4291-63-8

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Cladribine is chemically (2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol. Cladribine is supplied with detailed characterization data compliant with regulatory guideline. Cladribine can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Cladribine. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Cladribine Impurity 3
分子结构
CAS编号	244097-87-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2S,3R,5S)-5-(2,6-Diamino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
分子式	C10H14N6O3
分子量	266.3
InChI
InChI Key
Canonical SMILES	NC1=NC(N)=NC2=C1N=CN2[C@H]3O[C@@H](CO)[C@H](O)C3

英文名	Cladribine Monophosphate
分子结构
CAS编号	104959-31-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	Sodium ((2R,3S,5R)-5-(6-amino-2-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl hydrogen phosphate
分子式	C10H12ClN5O6P : Na
分子量	364.7 : 23.0
InChI
InChI Key
Canonical SMILES	NC1=C(N=CN2[C@@H]3O[C@H](COP(O)([O-])=O)[C@@H](O)C3)C2=NC(Cl)=N1.[Na+]

英文名	Cladribine Impurity 6
分子结构
CAS编号	136834-39-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Chloro-9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-ol
分子式	C10H11ClN4O4
分子量	286.7
InChI
InChI Key
Canonical SMILES	OC[C@@H]1[C@H](C[C@H](N2C=NC3=C(N=C(Cl)N=C32)O)O1)O

英文名	Cladribine Impurity 4
分子结构
CAS编号	106867-30-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	((2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-3-hydroxytetrahydrofuran-2-yl)methyl tetrahydrogen triphosphate
分子式	C10H15ClN5O12P3
分子量	525.6
InChI
InChI Key
Canonical SMILES	O[C@@H](C[C@H](N1C=NC2=C(N=C(Cl)N=C21)N)O3)[C@H]3COP(O)(OP(O)(OP(O)(O)=O)=O)=O

英文名	Cladribine 13C5
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl-13C)tetrahydrofuran-3-ol-2,3,4,5-13C4
分子式	C513C5H12ClN5O3
分子量	290.6
InChI
InChI Key
Canonical SMILES	O[13C@@H]1[13C@@H]([13CH2]O)O[13C@@H](N2C=NC3=C(N)N=C(Cl)N=C23)[13CH2]1

英文名	Cladribine Impurity 5
分子结构
CAS编号	13368-14-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Chloro-7H-purin-6-ol
分子式	C5H3ClN4O
分子量	170.6
InChI
InChI Key
Canonical SMILES	OC1=C2NC=NC2=NC(Cl)=N1

英文名	Cladribine Mono Benzoate Impurity
分子结构
CAS编号	152463-98-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetra hydrofuran-3-yl-4-methyl benzoate
分子式	C18H18ClN5O4
分子量	403.8
InChI
InChI Key
Canonical SMILES	O=C(O[C@@H]1[C@@H](CO)O[C@@H](N2C=NC3=C(N)N=C(Cl)N=C23)C1)C4=CC=C(C)C=C4

英文名	Cladribine Impurity 1
分子结构
CAS编号	172792-37-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3S,5R)-5-(6-Amino-2-chloro-7H-purin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
分子式	C10H12ClN5O3
分子量	285.7
InChI
InChI Key
Canonical SMILES	O[C@@H](C1)[C@@H](CO)O[C@H]1N2C=NC3=C2C(N)=NC(Cl)=N3

英文名	Cladribine Impurity 2
分子结构
CAS编号	3413-66-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3S,5S)-5-(6-Amino-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
分子式	C10H13N5O3
分子量	251.2
InChI
InChI Key
Canonical SMILES	O[C@@H]1[C@@H](CO)O[C@H](N2C=NC3=C(N)N=CN=C23)C1

英文名	Cladribine
分子结构
CAS编号	4291-63-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3S,5R)-5-(6-Amino-2-chloro-9H-purin-9-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol
分子式	C10H12ClN5O3
分子量	285.7
InChI
InChI Key
Canonical SMILES	NC1=C(N=CN2[C@@H]3O[C@H](CO)[C@@H](O)C3)C2=NC(Cl)=N1