N-Boc Crizotinib CAS#: 877399-51-4

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 N-Boc Crizotinib
分子结构
CAS编号 877399-51-4
EINECS Number
MDL Number
Beilstein Registry Number
别名 Tert-butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
分子式 C26H30Cl2FN5O3
分子量 550.5
InChI
InChI Key
Canonical SMILES C[C@H](C(C(Cl)=CC=C1F)=C1Cl)OC2=CC(C3=CN(C(CC4)CCN4C(OC(C)(C)C)=O)N=C3)=CN=C2N

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
N-Boc Crizotinib is chemically Tert-butyl (R)-4-(4-(6-amino-5-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate. N-Boc Crizotinib is supplied with detailed characterization data compliant with regulatory guideline. N-Boc Crizotinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

2-Keto Crizotinib CAS#: 1415558-82-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 2-Keto Crizotinib
分子结构
CAS编号 1415558-82-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 4-(4-(6-Amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-2-one
分子式 C21H20Cl2FN5O2
分子量 464.3
InChI
InChI Key
Canonical SMILES C[C@H](C(C(Cl)=CC=C1F)=C1Cl)OC2=CC(C3=CN(C(CCN4)CC4=O)N=C3)=CN=C2N

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
2-Keto Crizotinib is chemically 4-(4-(6-Amino-5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-3-yl)-1H-pyrazol-1-yl)piperidin-2-one. 2-Keto Crizotinib is supplied with detailed characterization data compliant with regulatory guideline. 2-Keto Crizotinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib Impurity 6 CAS#: 3026867-46-6

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib Impurity 6
分子结构
CAS编号 3026867-46-6
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine
分子式 C16H13Cl2FN4O
分子量 367.2
InChI
InChI Key
Canonical SMILES NC1=NC=C(C2=CNN=C2)C=C1O[C@@H](C3=C(Cl)C=CC(F)=C3Cl)C

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib Impurity 6 is chemically (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1H-pyrazol-4-yl)pyridin-2-amine. Crizotinib Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib Impurity 5 CAS#: 877399-74-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib Impurity 5
分子结构
CAS编号 877399-74-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 Tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate
分子式 C19H32BN3O4
分子量 377.3
InChI
InChI Key
Canonical SMILES O=C(N1CCC(CC1)N2N=CC(B3OC(C)(C(C)(C)O3)C)=C2)OC(C)(C)C

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib Impurity 5 is chemically Tert-butyl 4-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)piperidine-1-carboxylate. Crizotinib Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

(R)-Crizotinib-D5 CAS#: 1395950-84-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 (R)-Crizotinib-D5
分子结构
CAS编号 1395950-84-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl-3,3,4,5,5-d5)-1H-pyrazol-4-yl)pyridin-2-amine
分子式 C21H17D5Cl2FN5O
分子量 455.4
InChI
InChI Key
Canonical SMILES C[C@@H](OC1=CC(C2=CN(N=C2)C3([2H])C([2H])([2H])CNCC3([2H])[2H])=CN=C1N)C4=C(Cl)C(F)=CC=C4Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
(R)-Crizotinib-D5 is chemically (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl-3,3,4,5,5-d5)-1H-pyrazol-4-yl)pyridin-2-amine. It is also known as Crizotinib D5. (R)-Crizotinib-D5 is supplied with detailed characterization data compliant with regulatory guideline. (R)-Crizotinib-D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib Impurity 4 CAS#: 877397-71-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib Impurity 4
分子结构
CAS编号 877397-71-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
分子式 C13H11Cl2FN2O
分子量 301.1
InChI
InChI Key
Canonical SMILES NC1=NC=CC=C1O[C@@H](C2=C(Cl)C=CC(F)=C2Cl)C

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib Impurity 4 is chemically (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine. Crizotinib Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib S-Isomer CAS#: 1374356-45-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib S-Isomer
分子结构
CAS编号 1374356-45-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
分子式 C21H22Cl2FN5O
分子量 450.3
InChI
InChI Key
Canonical SMILES NC1=NC=C(C2=CN(C3CCNCC3)N=C2)C=C1O[C@H](C4=C(Cl)C=CC(F)=C4Cl)C

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib S-Isomer is chemically (S)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine. Crizotinib S-Isomer is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib S-Isomer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib Impurity 2 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib Impurity 2
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine
分子式 C24H28Cl2FN5O
分子量 492.4
InChI
InChI Key
Canonical SMILES ClC1=C([C@@H](C)OC2=C(N)N=CC(C3=CN(C4CCN(C(C)C)CC4)N=C3)=C2)C(Cl)=C(F)C=C1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib Impurity 2 is chemically (R)-3-(1-(2,6-Dichloro-3-fluorophenyl)ethoxy)-5-(1-(1-isopropylpiperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine. Crizotinib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib CAS#: 877399-52-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib
分子结构
CAS编号 877399-52-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine
分子式 C21H22Cl2FN5O
分子量 450.3
InChI
InChI Key
Canonical SMILES C[C@H](C(C(Cl)=CC=C1F)=C1Cl)OC2=CC(C3=CN(C4CCNCC4)N=C3)=CN=C2N

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib is chemically 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-pyridinamine. Crizotinib is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Crizotinib Impurity 3 CAS#: 877399-00-3

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Crizotinib Impurity 3
分子结构
CAS编号 877399-00-3
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine
分子式 C13H10BrCl2FN2O
分子量 380.0
InChI
InChI Key
Canonical SMILES C[C@H](C(C(Cl)=CC=C1F)=C1Cl)OC(C=C(Br)C=N2)=C2N

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Crizotinib Impurity 3 is chemically (R)-5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)pyridin-2-amine. Crizotinib Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Crizotinib Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Crizotinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.