M31-Dabrafenib CAS#: 1613724-51-8

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 M31-Dabrafenib
分子结构
CAS编号 1613724-51-8
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(prop-1-en-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
分子式 C22H16F3N5O2S2
分子量 503.5
InChI
InChI Key
Canonical SMILES FC(C(N[S](=O)(C(C(F)=CC=C1)=C1F)=O)=CC=C2)=C2C3=C(C4=NC(N)=NC=C4)SC(C(C)=C)=N3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
M31-Dabrafenib is chemically N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(prop-1-en-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide. M31-Dabrafenib is supplied with detailed characterization data compliant with regulatory guideline. M31-Dabrafenib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Diamine Sulfonamide Impurity CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Diamine Sulfonamide Impurity
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(2-Amino-3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)phenyl)-2,6-difluorobenzenesulfonamide
分子式 C23H22F2N6O2S2
分子量 516.6
InChI
InChI Key
Canonical SMILES O=S(C1=C(F)C=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=NC=C4)SC(C(C)(C)C)=N3)=C2N)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Diamine Sulfonamide Impurity is chemically N-(2-Amino-3-(5-(2-aminopyrimidin-4-yl)-2-(tert-butyl)thiazol-4-yl)phenyl)-2,6-difluorobenzenesulfonamide. Dabrafenib Diamine Sulfonamide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Diamine Sulfonamide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Impurity 11 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Impurity 11
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(3-(5-(2-Aminopyrimidin-4-yl)-2-isopropylthiazol-4-yl)-2-fluorophenyl)benzenesulfonamide
分子式 C22H20FN5O2S2
分子量 469.6
InChI
InChI Key
Canonical SMILES FC(C(N[S](=O)(C1=CC=CC=C1)=O)=CC=C2)=C2C3=C(C4=NC(N)=NC=C4)SC(C(C)C)=N3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Impurity 11 is chemically N-(3-(5-(2-Aminopyrimidin-4-yl)-2-isopropylthiazol-4-yl)-2-fluorophenyl)benzenesulfonamide. Dabrafenib Impurity 11 is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Impurity 11 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Di-N-Oxide Impurity CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Di-N-Oxide Impurity
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 5-(2-Amino-1-oxidopyrimidin-4-yl)-2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazole 3-oxide
分子式 C23H20F3N5O4S2
分子量 551.6
InChI
InChI Key
Canonical SMILES FC(C(N[S](=O)(C1=C(F)C=CC=C1F)=O)=CC=C2)=C2C3=C(C4=NC(N)=[N+]([O-])C=C4)SC(C(C)(C)C)=[N+]3[O-]

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Di-N-Oxide Impurity is chemically 5-(2-Amino-1-oxidopyrimidin-4-yl)-2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazole 3-oxide. Dabrafenib Di-N-Oxide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Di-N-Oxide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Methoxy Impurity CAS#: 1907654-22-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Methoxy Impurity
分子结构
CAS编号 1907654-22-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(3-(2-(Tert-butyl)-5-(2-methoxypyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
分子式 C24H21F3N4O3S2
分子量 534.6
InChI
InChI Key
Canonical SMILES O=S(C1=C(F)C=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(OC)=NC=C4)SC(C(C)(C)C)=N3)=C2F)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Methoxy Impurity is chemically N-(3-(2-(Tert-butyl)-5-(2-methoxypyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide. Dabrafenib Methoxy Impurity is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Methoxy Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib N-Oxide Impurity CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib N-Oxide Impurity
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 2-Amino-4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidine 1-oxide
分子式 C23H20F3N5O3S2
分子量 535.6
InChI
InChI Key
Canonical SMILES O=S(C1=C(F)C=CC=C1F)(NC2=CC=CC(C3=C(C4=NC(N)=[N+]([O-])C=C4)SC(C(C)(C)C)=N3)=C2F)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib N-Oxide Impurity is chemically 2-Amino-4-(2-(tert-butyl)-4-(3-((2,6-difluorophenyl)sulfonamido)-2-fluorophenyl)thiazol-5-yl)pyrimidine 1-oxide. Dabrafenib N-Oxide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib N-Oxide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Impurity 9 CAS#: 1195768-23-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Impurity 9
分子结构
CAS编号 1195768-23-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
分子式 C23H18ClF3N4O2S2
分子量 539.0
InChI
InChI Key
Canonical SMILES FC1=C(C=CC=C1N[S](=O)(C(C(F)=CC=C2)=C2F)=O)C3=C(C4=NC(Cl)=NC=C4)SC(C(C)(C)C)=N3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Impurity 9 is chemically N-(3-(2-(Tert-butyl)-5-(2-chloropyrimidin-4-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide. Dabrafenib Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Impurity 6 CAS#: 5129-25-9

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Impurity 6
分子结构
CAS编号 5129-25-9
EINECS Number
MDL Number
Beilstein Registry Number
别名 Methyl 3-amino-2-methoxybenzoate
分子式 C9H11NO3
分子量 181.2
InChI
InChI Key
Canonical SMILES O=C(OC)C1=CC=CC(N)=C1OC

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1187927-19-0 (HCl salt)
Use Pattern
Dabrafenib Impurity 6 is chemically Methyl 3-amino-2-methoxybenzoate. Dabrafenib Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Dabrafenib Impurity 14 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Dabrafenib Impurity 14
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (E)-N-(3-(1,3-diaminoprop-1-en-1-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
分子式 C15H14F3N3O2S
分子量 357.4
InChI
InChI Key
Canonical SMILES FC(C(N[S](=O)(C1=C(F)C=CC=C1F)=O)=CC=C2)=C2/C(N)=CCN

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Dabrafenib Impurity 14 is chemically (E)-N-(3-(1,3-diaminoprop-1-en-1-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide. Dabrafenib Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Dabrafenib Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Hydroxy Dabrafenib CAS#: 1195767-77-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Hydroxy Dabrafenib
分子结构
CAS编号 1195767-77-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
分子式 C23H20F3N5O3S2
分子量 535.6
InChI
InChI Key
Canonical SMILES FC(C(N[S](=O)(C(C(F)=CC=C1)=C1F)=O)=CC=C2)=C2C3=C(C4=NC(N)=NC=C4)SC(C(C)(CO)C)=N3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Hydroxy Dabrafenib is chemically N-(3-(5-(2-Aminopyrimidin-4-yl)-2-(1-hydroxy-2-methylpropan-2-yl)thiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide. Hydroxy Dabrafenib is supplied with detailed characterization data compliant with regulatory guideline. Hydroxy Dabrafenib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Dabrafenib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.