Darolutamide • ChemWhat中文网 | 凯望化学与生物数据库

Darolutamide Impurity 4 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Impurity 4 is chemically (E)-4,4′-(1,3-Dihydroxybut-1-ene-1,3-diyl)bis(2-chlorobenzonitrile). Darolutamide Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Pyrazol butyl Impurity CAS#: 2415967-06-3

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Pyrazol butyl Impurity is chemically (S)-Tert-butyl (1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)carbamate. Darolutamide Pyrazol butyl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Pyrazol butyl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Pyrazol benzonitrile Impurity CAS#: 1297537-37-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Pyrazol benzonitrile Impurity is chemically 2-Chloro-4(1H-pyrazol-3-yl) benzonitrile. Darolutamide Pyrazol benzonitrile Impurity is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Pyrazol benzonitrile Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Darolutamide Pyrazol benzonitrile Impurity CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Darolutamide Pyrazol benzonitrile Impurity is chemically 2-Chloro-4-(1-nitroso-1H-pyrazol-3-yl)benzonitrile. N-Nitroso Darolutamide Pyrazol benzonitrile Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Darolutamide Pyrazol benzonitrile Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Impurity 2 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Impurity 2 is chemically N-(2-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propyl)-N-(2-formylphenyl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide. Darolutamide Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Impurity 3 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Impurity 3 is chemically N-(1-(3-(3-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide. Darolutamide Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide D4 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide D4 is chemically N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl-2,3,3,3-d4)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide. Darolutamide D4 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide D4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Nitroso Impurity 2 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Nitroso Impurity 2 is chemically (S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-nitroso-1H-pyrazole-3-carboxamide. Darolutamide Nitroso Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Nitroso Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Nitroso Impurity 1 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Nitroso Impurity 1 is chemically 5-Acetyl-1-nitroso-1H-pyrazole-3-carboxylic acid. Darolutamide Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Darolutamide Nitroso Impurity CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Darolutamide Nitroso Impurity is chemically N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1-nitroso-1H-pyrazole-3-carboxamide. Darolutamide Nitroso Impurity is supplied with detailed characterization data compliant with regulatory guideline. Darolutamide Nitroso Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Darolutamide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Darolutamide Impurity 4
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(E)-4,4′-(1,3-Dihydroxybut-1-ene-1,3-diyl)bis(2-chlorobenzonitrile)
分子式	C18H12Cl2N2O2
分子量	359.2
InChI
InChI Key
Canonical SMILES	CC(O)(C1=CC=C(C(Cl)=C1)C#N)/C=C(C2=CC=C(C(Cl)=C2)C#N)/O

英文名	Darolutamide Pyrazol butyl Impurity
分子结构
CAS编号	2415967-06-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	(S)-Tert-butyl (1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)carbamate
分子式	C18H21ClN4O2
分子量	360.8
InChI
InChI Key
Canonical SMILES	O=C(OC(C)(C)C)N[C@@H](C)CN1N=C(C2=CC=C(C#N)C(Cl)=C2)C=C1

英文名	Darolutamide Pyrazol benzonitrile Impurity
分子结构
CAS编号	1297537-37-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Chloro-4(1H-pyrazol-3-yl) benzonitrile
分子式	C10H6ClN3
分子量	203.6
InChI
InChI Key
Canonical SMILES	N#CC1=CC=C(C2=NNC=C2)C=C1Cl

英文名	N-Nitroso Darolutamide Pyrazol benzonitrile Impurity
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Chloro-4-(1-nitroso-1H-pyrazol-3-yl)benzonitrile
分子式	C10H5ClN4O
分子量	232.6
InChI
InChI Key
Canonical SMILES	N#CC1=CC=C(C2=NN(N=O)C=C2)C=C1Cl

英文名	Darolutamide Impurity 2
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(2-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propyl)-N-(2-formylphenyl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
分子式	C26H23ClN6O3
分子量	503.0
InChI
InChI Key
Canonical SMILES	O=CC1=CC=CC=C1N(CC(N2N=C(C3=CC=C(C#N)C(Cl)=C3)C=C2)C)C(C4=NNC(C(O)C)=C4)=O

英文名	Darolutamide Impurity 3
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(1-(3-(3-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
分子式	C29H24ClN9O2
分子量	566.0
InChI
InChI Key
Canonical SMILES	O=C(C1=NNC(C(O)C)=C1)NC(C)CN2N=C(C3=CC=C(C#N)C(N4N=C(C5=CC=C(C#N)C(Cl)=C5)C=C4)=C3)C=C2

英文名	Darolutamide D4
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl-2,3,3,3-d4)-5-(1-hydroxyethyl)-1H-pyrazole-3-carboxamide
分子式	C19H15D4ClN6O2
分子量	402.9
InChI
InChI Key
Canonical SMILES	O=C(C1=NNC(C(O)C)=C1)N[C@@]([2H])(C([2H])([2H])[2H])CN2N=C(C3=CC(Cl)=C(C#N)C=C3)C=C2

英文名	Darolutamide Nitroso Impurity 2
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(S)-5-Acetyl-N-(1-(3-(3-chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-1-nitroso-1H-pyrazole-3-carboxamide
分子式	C19H16ClN7O3
分子量	425.8
InChI
InChI Key
Canonical SMILES	O=C(C1=NN(N=O)C(C(C)=O)=C1)N[C@@H](C)CN2N=C(C3=CC=C(C#N)C(Cl)=C3)C=C2

英文名	Darolutamide Nitroso Impurity 1
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-Acetyl-1-nitroso-1H-pyrazole-3-carboxylic acid
分子式	C6H5N3O4
分子量	183.1
InChI
InChI Key
Canonical SMILES	OC(C1=NN(N=O)C(C(C)=O)=C1)=O

英文名	Darolutamide Nitroso Impurity
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-((S)-1-(3-(3-Chloro-4-cyanophenyl)-1H-pyrazol-1-yl)propan-2-yl)-5-(1-hydroxyethyl)-1-nitroso-1H-pyrazole-3-carboxamide
分子式	C19H18ClN7O3
分子量	427.8
InChI
InChI Key
Canonical SMILES	C[C@H](NC(C1=NN(N=O)C(C(O)C)=C1)=O)CN2N=C(C3=CC(Cl)=C(C#N)C=C3)C=C2