Diazepam • ChemWhat中文网 | 凯望化学与生物数据库

Diazepam Impurity 2 CAS#: 1021462-91-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	215370-63-1 (free base)

Use Pattern

Diazepam Impurity 2 is chemically (R)-N-(2-benzoyl-4-chlorophenyl)-1-benzylpyrrolidine-2-carboxamide hydrochloride. Diazepam Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Diazepam Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam Impurity 1 CAS#: 36020-94-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam Impurity 1 is chemically 2-Amino-N-(2-benzoyl-4-chlorophenyl)-N-methylacetamide. Diazepam Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Diazepam Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam EP Impurity C CAS#: 5220-02-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam EP Impurity C is chemically 3-Amino-6-chloro-1-methyl-4-phenylquinolin-2(1H)-one (as per EP) ; 3-Amino-6-chloro-1-methyl-4-phenylcarbostyril (as per USP). It is also known as Diazepam USP Related Compound B. Diazepam EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Diazepam EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam EP Impurity D CAS#: 1022-13-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam EP Impurity D is chemically [5-Chloro-2-(methylamino)phenyl]phenylmethanone (as per EP) ; 2-Methylamino-5-chlorobenzophenone (as per USP). It is also known as Diazepam USP Related Compound A. Diazepam EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Diazepam EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam EP Impurity F CAS#: 31269-33-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam EP Impurity F is chemically 7-Chloro-2-methoxy-5-phenyl-3H-1,4-benzodiazepine. Diazepam EP Impurity F is supplied with detailed characterization data compliant with regulatory guideline. Diazepam EP Impurity F can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam EP Impurity A CAS#: 1088-11-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	41631-10-1 (HCl salt) ; 24139-22-8 (XHCl salt)

Use Pattern

Diazepam EP Impurity A is chemically 7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (as per EP) ; 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (as per USP). It is also known as Nordazepam (EP & USP). Diazepam EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Diazepam EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam Dimer Impurity 1 CAS#: 3646-61-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam Dimer Impurity 1 is chemically (5Z,11Z)-2,8-dichloro-6,12-diphenyldibenzo[b,f][1,5]diazocine. Diazepam Dimer Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Diazepam Dimer Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam D5 CAS#: 65854-76-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Diazepam D5 is chemically 7-Chloro-1-methyl-5-(phenyl-d5)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one. Diazepam D5 is supplied with detailed characterization data compliant with regulatory guideline. Diazepam D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Diazepam EP Impurity D CAS#: 51145-18-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Diazepam EP Impurity D is chemically N-(2-Benzoyl-4-chlorophenyl)-N-methylnitrous amide. N-Nitroso Diazepam EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Diazepam EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diazepam CAS#: 439-14-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	52468-36-7 (HCl salt)

Use Pattern

Diazepam is chemically 7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (as per EP) ; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl- (as per USP). Diazepam is supplied with detailed characterization data compliant with regulatory guideline. Diazepam can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Diazepam. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Diazepam Impurity 2
分子结构
CAS编号	1021462-91-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	(R)-N-(2-benzoyl-4-chlorophenyl)-1-benzylpyrrolidine-2-carboxamide hydrochloride
分子式	C25H23ClN2O2 : HCl
分子量	418.9 : 36.5
InChI
InChI Key
Canonical SMILES	O=C([C@@H]1N(CC2=CC=CC=C2)CCC1)NC3=CC=C(Cl)C=C3C(C4=CC=CC=C4)=O.Cl

英文名	Diazepam Impurity 1
分子结构
CAS编号	36020-94-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Amino-N-(2-benzoyl-4-chlorophenyl)-N-methylacetamide
分子式	C16H15ClN2O2
分子量	302.8
InChI
InChI Key
Canonical SMILES	O=C(C1=CC=CC=C1)C(C=C2Cl)=C(C=C2)N(C)C(CN)=O

英文名	Diazepam EP Impurity C
分子结构
CAS编号	5220-02-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-Amino-6-chloro-1-methyl-4-phenylquinolin-2(1H)-one (as per EP) ; 3-Amino-6-chloro-1-methyl-4-phenylcarbostyril (as per USP)
分子式	C16H13ClN2O
分子量	284.7
InChI
InChI Key
Canonical SMILES	ClC1=CC(C(C2=CC=CC=C2)=C(N)C(N3C)=O)=C3C=C1

英文名	Diazepam EP Impurity D
分子结构
CAS编号	1022-13-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	[5-Chloro-2-(methylamino)phenyl]phenylmethanone (as per EP) ; 2-Methylamino-5-chlorobenzophenone (as per USP)
分子式	C14H12ClNO
分子量	245.7
InChI
InChI Key
Canonical SMILES	ClC1=CC(C(C2=CC=CC=C2)=O)=C(NC)C=C1

英文名	Diazepam EP Impurity F
分子结构
CAS编号	31269-33-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-Chloro-2-methoxy-5-phenyl-3H-1,4-benzodiazepine
分子式	C16H13ClN2O
分子量	284.7
InChI
InChI Key
Canonical SMILES	ClC1=CC(C(C2=CC=CC=C2)=NCC(OC)=N3)=C3C=C1

英文名	Diazepam EP Impurity A
分子结构
CAS编号	1088-11-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-Chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (as per EP) ; 7-Chloro-1,3-dihydro-5-phenyl-2H-1,4-benzodiazepin-2-one (as per USP)
分子式	C15H11ClN2O
分子量	270.7
InChI
InChI Key
Canonical SMILES	ClC1=CC(C(C2=CC=CC=C2)=NCC(N3)=O)=C3C=C1

英文名	Diazepam Dimer Impurity 1
分子结构
CAS编号	3646-61-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	(5Z,11Z)-2,8-dichloro-6,12-diphenyldibenzo[b,f][1,5]diazocine
分子式	C26H16Cl2N2
分子量	427.3
InChI
InChI Key
Canonical SMILES	ClC1=CC2=C(C=C1)/N=C(C3=CC=CC=C3)C4=CC(Cl)=CC=C4/N=C2/C5=CC=CC=C5

英文名	Diazepam D5
分子结构
CAS编号	65854-76-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-Chloro-1-methyl-5-(phenyl-d5)-1,3-dihydro-2H-benzo[e][1,4]diazepin-2-one
分子式	C16H8D5ClN2O
分子量	289.8
InChI
InChI Key
Canonical SMILES	CN1C(C(C(C2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=NCC1=O)=C3)=CC=C3Cl

英文名	N-Nitroso Diazepam EP Impurity D
分子结构
CAS编号	51145-18-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(2-Benzoyl-4-chlorophenyl)-N-methylnitrous amide
分子式	C14H11ClN2O2
分子量	274.7
InChI
InChI Key
Canonical SMILES	O=NN(C1=CC=C(Cl)C=C1C(C2=CC=CC=C2)=O)C

英文名	Diazepam
分子结构
CAS编号	439-14-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-Chloro-1-methyl-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (as per EP) ; 2H-1,4-Benzodiazepin-2-one, 7-chloro-1,3-dihydro-1-methyl-5-phenyl- (as per USP)
分子式	C16H13ClN2O
分子量	284.7
InChI
InChI Key
Canonical SMILES	ClC1=CC(C(C2=CC=CC=C2)=NCC(N3C)=O)=C3C=C1