Fosaprepitant Impurity 15 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 15
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 Dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazole-1,4(5H)-diyl)bis(hydrogen phosphonate)
分子式 C37H35F7N4O9P2
分子量 874.6
InChI
InChI Key
Canonical SMILES O=C(N(P(OCC1=CC=CC=C1)(O)=O)C(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@H](C)C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)OCC2)=N5)N5P(OCC6=CC=CC=C6)(O)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Impurity 15 is chemically Dibenzyl (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1H-1,2,4-triazole-1,4(5H)-diyl)bis(hydrogen phosphonate). Fosaprepitant Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Phosphoryl Impurity CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Phosphoryl Impurity
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic phosphoric anhydride
分子式 C23H23F7N4O9P2
分子量 694.4
InChI
InChI Key
Canonical SMILES O=P(O)(OP(N1NC(CN2[C@@H](C3=CC=C(F)C=C3)[C@@H](O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)OCC2)=NC1=O)(O)=O)O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Phosphoryl Impurity is chemically (3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic phosphoric anhydride. Fosaprepitant Phosphoryl Impurity is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Phosphoryl Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 8 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 8
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 5-(((2R,3S)-3-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one
分子式 C23H21F7N4O3
分子量 534.4
InChI
InChI Key
Canonical SMILES O=C1NNC(CN2[C@@H](O[C@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)[C@@H](C4=CC=C(F)C=C4)OCC2)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Impurity 8 is chemically 5-(((2R,3S)-3-((S)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-2-(4-fluorophenyl)morpholino)methyl)-1,2-dihydro-3H-1,2,4-triazol-3-one. Fosaprepitant Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 12 CAS#: 327623-36-9

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 12
分子结构
CAS编号 327623-36-9
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one
分子式 C21H19F6NO3
分子量 447.4
InChI
InChI Key
Canonical SMILES O=C1N(CC2=CC=CC=C2)CCO[C@H]1O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Impurity 12 is chemically (S)-4-Benzyl-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)morpholin-3-one. Fosaprepitant Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 10 CAS#: 172673-19-7

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 10
分子结构
CAS编号 172673-19-7
EINECS Number
MDL Number
Beilstein Registry Number
别名 (3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phosphonic acid
分子式 C23H22F7N4O6P
分子量 614.4
InChI
InChI Key
Canonical SMILES FC(F)(F)C1=CC(C(F)(F)F)=CC([C@@H](C)O[C@H]2OCCN(CC(N3P(O)(O)=O)=NNC3=O)[C@H]2C4=CC=C(F)C=C4)=C1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 172822-02-5 (2K salt)
Use Pattern
Fosaprepitant Impurity 10 is chemically (3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-1,5-dihydro-4H-1,2,4-triazol-4-yl)phosphonic acid. Fosaprepitant Impurity 10 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 14 CAS#: 990-91-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 14
分子结构
CAS编号 990-91-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 Tetrabenzyl diphosphate
分子式 C28H28O7P2
分子量 538.5
InChI
InChI Key
Canonical SMILES O=P(OP(OCC1=CC=CC=C1)(OCC2=CC=CC=C2)=O)(OCC3=CC=CC=C3)OCC4=CC=CC=C4

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Impurity 14 is chemically Tetrabenzyl diphosphate. Fosaprepitant Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 16 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 16
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl phosphate
分子式 C23H22F7N4O7P : C7H17NO5
分子量 630.4 : 195.2
InChI
InChI Key
Canonical SMILES O=P(O)(O)ON1NC(CN2[C@H](C3=CC=C(F)C=C3)[C@H](O[C@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)OCC2)=NC1=O.O[C@H]([C@H]([C@@H]([C@@H](CO)O)O)O)CNC

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1350288-79-7 (free base)
Use Pattern
Fosaprepitant Impurity 16 is chemically (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol 3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-2,5-dihydro-1H-1,2,4-triazol-1-yl phosphate. Fosaprepitant Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Impurity 13 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Impurity 13
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (4-benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate
分子式 C31H31F6N4O6P : C7H17NO5
分子量 700.6 : 195.2
InChI
InChI Key
Canonical SMILES O=C1N(CC2=CC=CC=C2)C(CN3[C@@H](C4=CC=C(C)C=C4)[C@@H](O[C@@H](C5=CC(C(F)(F)F)=CC(C(F)(F)F)=C5)C)OCC3)=NN1P(O)(O)=O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Impurity 13 is chemically (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol (4-benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate. Fosaprepitant Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Ester Impurity CAS#: 1803189-49-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Ester Impurity
分子结构
CAS编号 1803189-49-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 Methyl (Z)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
分子式 C24H25F7N4O4
分子量 566.5
InChI
InChI Key
Canonical SMILES O=C(N/N=C(N)/CN1[C@@H](C2=CC=C(F)C=C2)[C@@H](O[C@@H](C3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)C)OCC1)OC

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Fosaprepitant Ester Impurity is chemically Methyl (Z)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate. Fosaprepitant Ester Impurity is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Ester Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Fosaprepitant Potassium salt CAS#: 172822-03-6

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Fosaprepitant Potassium salt
分子结构
CAS编号 172822-03-6
EINECS Number
MDL Number
Beilstein Registry Number
别名 (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid Potassium salt
分子式 C23H22F7N4O6P : 2(K)
分子量 614.4 : 2(39.1)
InChI
InChI Key
Canonical SMILES O=C1NC(CN(CCO2)[C@@H](C3=CC=C(F)C=C3)[C@H]2O[C@@H](C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C)=NN1[P](O)(O)=O.[2K]

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 172673-20-0 (free base) ; 265121-04-8 (Dimeglumine)
Use Pattern
Fosaprepitant Potassium salt is chemically (3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid Potassium salt. Fosaprepitant Potassium salt is supplied with detailed characterization data compliant with regulatory guideline. Fosaprepitant Potassium salt can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Fosaprepitant. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.