Irinotecan Nitroso Impurity 1 CAS#: 2639422-25-4

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan Nitroso Impurity 1
分子结构
CAS编号 2639422-25-4
EINECS Number
MDL Number
Beilstein Registry Number
别名 1′-Nitroso-1,4′-bipiperidine
分子式 C10H19N3O
分子量 197.3
InChI
InChI Key
Canonical SMILES O=NN1CCC(N2CCCCC2)CC1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Irinotecan Nitroso Impurity 1 is chemically 1′-Nitroso-1,4′-bipiperidine. Irinotecan Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan EP Impurity D CAS#: 7689-03-4

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan EP Impurity D
分子结构
CAS编号 7689-03-4
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione (as per USP)
分子式 C20H16N2O4
分子量 348.4
InChI
InChI Key
Canonical SMILES CC[C@](C(C=C1N2CC3=CC4=CC=CC=C4N=C13)=C5C2=O)(C(OC5)=O)O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 72517-83-0 (Na salt)
Use Pattern
Irinotecan EP Impurity D is chemically (S)-4-Ethyl-4-hydroxy-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quin oline-3,14(4H,12H)-dione (as per USP). It is also known as Camptothecin. Irinotecan EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan EP Impurity M (HCl salt) CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan EP Impurity M (HCl salt)
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride
分子式 C33H38N4O7 : HCl
分子量 602.7 : 36.5
InChI
InChI Key
Canonical SMILES OC(C(C1=NC2=CC=C(OC(N3CCC(N4CCCCC4)CC3)=O)C=C52)=C5CC)N6C1=CC([C@](O)7CC)=C(COC7=O)C6=O.Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 185336-12-3 (free base)
Use Pattern
Irinotecan EP Impurity M (HCl salt) is chemically (4S)-4,11-diethyl-4,12-dihydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate hydrochloride. It is also known as 12-Hydroxy Irinotecan. Irinotecan EP Impurity M (HCl salt) is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity M (HCl salt) can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan USP Related Compound C CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan USP Related Compound C
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride (as per USP)
分子式 C32H36N4O6 : HCl
分子量 572.7 : 36.5
InChI
InChI Key
Canonical SMILES O=C(N1CCC(N2CCCCC2)CC1)OC3=CC=C4N=C5C(CN6C(C(COC(C7(O)C)=O)=C7C=C65)=O)=C(CC)C4=C3.Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Irinotecan USP Related Compound C is chemically 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl (1,4′-bipiperidine)-1′-carboxylate hydrochloride (as per USP). Irinotecan USP Related Compound C is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan USP Related Compound C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

SN-38 Carboxylate Disodium Salt CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 SN-38 Carboxylate Disodium Salt
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate
分子式 C22H20N2O6 : 2(Na)
分子量 408.4 : 2(23.0)
InChI
InChI Key
Canonical SMILES O=C1N(CC2=C3N=C(C=CC([O-])=C4)C4=C2CC)C3=CC([C@](CC)(O)C([O-])=O)=C1CO.[Na+].[Na+]

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 142677-15-4 (free base)
Use Pattern
SN-38 Carboxylate Disodium Salt is chemically Sodium (S)-2-(12-ethyl-8-(hydroxymethyl)-2-oxido-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoate. SN-38 Carboxylate Disodium Salt is supplied with detailed characterization data compliant with regulatory guideline. SN-38 Carboxylate Disodium Salt can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan Acid CAS#: 142706-06-7

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan Acid
分子结构
CAS编号 142706-06-7
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-(2-(([1,4′-bipiperidine]-1′-carbonyl)oxy)-12-ethyl-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid
分子式 C33H40N4O7
分子量 604.7
InChI
InChI Key
Canonical SMILES O=C1N2CC3=C(CC)C4=CC(OC(N5CCC(N6CCCCC6)CC5)=O)=CC=C4N=C3C2=CC([C@@](O)(CC)C(O)=O)=C1CO

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1329502-92-2 (Na salt) ; 509107-82-8 (HCl salt) ; 2216738-99-5 (disodium salt)
Use Pattern
Irinotecan Acid is chemically (S)-2-(2-(([1,4′-bipiperidine]-1′-carbonyl)oxy)-12-ethyl-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid. Irinotecan Acid is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Acid can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan EP Impurity H CAS#: 1608617-71-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan EP Impurity H
分子结构
CAS编号 1608617-71-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4S)-11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate (as per EP)
分子式 C32H36N4O6
分子量 572.7
InChI
InChI Key
Canonical SMILES O[C@@](C(OC1)=O)(C)C2=C1C(N3C(C4=NC5=CC=C(OC(N6CCC(N7CCCCC7)CC6)=O)C=C5C(CC)=C4C3)=C2)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1608463-33-7 (HCl salt)
Use Pattern
Irinotecan EP Impurity H is chemically (4S)-11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl 1,4′-bipiperidine-1′-carboxylate (as per EP). It is also known as 4-Methyl Irinotecan Analogue (EP). Irinotecan EP Impurity H is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan Impurity 7 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan Impurity 7
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 2′-Methoxy-[1,4′-bipiperidine]-1′-carbonyl chloride
分子式 C12H21ClN2O2
分子量 260.8
InChI
InChI Key
Canonical SMILES COC(C1)N(C(Cl)=O)CCC1N2CCCCC2

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Irinotecan Impurity 7 is chemically 2′-Methoxy-[1,4′-bipiperidine]-1′-carbonyl chloride. Irinotecan Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan Impurity 10 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan Impurity 10
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 11-Ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate
分子式 C31H34N4O5
分子量 542.6
InChI
InChI Key
Canonical SMILES O=C(OC1=CC=C(N=C(C(N2C3)=CC(CC(OC4)=O)=C4C2=O)C3=C5CC)C5=C1)N(CC6)CCC6N7CCCCC7

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Irinotecan Impurity 10 is chemically 11-Ethyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate. Irinotecan Impurity 10 is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan Impurity 10 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Irinotecan CAS#: 97682-44-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Irinotecan
分子结构
CAS编号 97682-44-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate
分子式 C33H38N4O6
分子量 586.7
InChI
InChI Key
Canonical SMILES O=C(OC(C=C1)=CC2=C1N=C(C(N3C4)=CC([C@@](O)(CC)C(OC5)=O)=C5C3=O)C4=C2CC)N(CC6)CCC6N7CCCCC7

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 136572-09-3 (HCl trihydrate) ; 100286-90-6 (HCl salt)
Use Pattern
Irinotecan is chemically (S)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl [1,4′-bipiperidine]-1′-carboxylate. Irinotecan is supplied with detailed characterization data compliant with regulatory guideline. Irinotecan can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Irinotecan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.