Leflunomide • ChemWhat中文网 | 凯望化学与生物数据库

Leflunomide Impurity 3 CAS#: 2772495-33-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide Impurity 3 is chemically 5-Methyl-N-(4-((4-(trifluoromethyl)phenyl)carbamoyl)phenyl)isoxazole-4-carboxamide. Leflunomide Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide Impurity 4 CAS#: 19788-35-3

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide Impurity 4 is chemically Methyl 5-methylisoxazole-3-carboxylate. Leflunomide Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide Impurity 2 CAS#: 17153-20-7

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide Impurity 2 is chemically 3-Methylisoxazole-4-carboxylic Acid. It is also known as Earlier CAT No = SZ-L032017. Leflunomide Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide EP Impurity H CAS#: 24522-30-3

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide EP Impurity H is chemically 2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide. Leflunomide EP Impurity H is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity H can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide EP Impurity A CAS#: 455-14-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide EP Impurity A is chemically 4-(Trifluoromethyl)aniline. It is also known as Leflunomide USP Related Compound A. Leflunomide EP Impurity A is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide Impurity 1 CAS#: 419534-37-5

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide Impurity 1 is chemically 2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide . Leflunomide Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide Metabolite Ethyl Analog CAS#: 2734292-21-6

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide Metabolite Ethyl Analog is chemically (Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)pent-2-enamide. Leflunomide Metabolite Ethyl Analog is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide Metabolite Ethyl Analog can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide EP Impurity D CAS#: 42831-50-5

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide EP Impurity D is chemically 5-Methylisoxazole-4-carboxylic acid. Leflunomide EP Impurity D is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity D can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide EP Impurity E CAS#: 208401-20-1

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide EP Impurity E is chemically 3-Methyl-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide. Leflunomide EP Impurity E is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity E can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leflunomide EP Impurity C CAS#: 61643-23-0

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Leflunomide EP Impurity C is chemically 5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide. It is also known as Leflunomide USP Related Compound C. Leflunomide EP Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Leflunomide EP Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leflunomide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Leflunomide Impurity 3
分子结构
CAS编号	2772495-33-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-Methyl-N-(4-((4-(trifluoromethyl)phenyl)carbamoyl)phenyl)isoxazole-4-carboxamide
分子式	C19H14F3N3O3
分子量	389.3
InChI
InChI Key
Canonical SMILES	O=C(NC1=CC=C(C(F)(F)F)C=C1)C2=CC=C(NC(C3=C(C)ON=C3)=O)C=C2

英文名	Leflunomide Impurity 4
分子结构
CAS编号	19788-35-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl 5-methylisoxazole-3-carboxylate
分子式	C6H7NO3
分子量	141.1
InChI
InChI Key
Canonical SMILES	CC1=CC(C(OC)=O)=NO1

英文名	Leflunomide Impurity 2
分子结构
CAS编号	17153-20-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-Methylisoxazole-4-carboxylic Acid
分子式	C5H5NO3
分子量	127.1
InChI
InChI Key
Canonical SMILES	O=C(C1=CON=C1C)O

英文名	Leflunomide EP Impurity H
分子结构
CAS编号	24522-30-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Cyano-N-(4-(trifluoromethyl)phenyl)acetamide
分子式	C10H7F3N2O
分子量	228.2
InChI
InChI Key
Canonical SMILES	O=C(CC#N)NC1=CC=C(C(F)(F)F)C=C1

英文名	Leflunomide EP Impurity A
分子结构
CAS编号	455-14-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(Trifluoromethyl)aniline
分子式	C7H6F3N
分子量	161.1
InChI
InChI Key
Canonical SMILES	NC1=CC=C(C(F)(F)F)C=C1

英文名	Leflunomide Impurity 1
分子结构
CAS编号	419534-37-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Cyano-N-[2-(trifluoromethyl)phenyl]acetamide
分子式	C10H7F3N2O
分子量	228.2
InChI
InChI Key
Canonical SMILES	FC(F)(C(C=CC=C1)=C1NC(CC#N)=O)F

英文名	Leflunomide Metabolite Ethyl Analog
分子结构
CAS编号	2734292-21-6
EINECS Number
MDL Number
Beilstein Registry Number
别名	(Z)-2-Cyano-3-hydroxy-N-(4-(trifluoromethyl)phenyl)pent-2-enamide
分子式	C13H11F3N2O2
分子量	284.2
InChI
InChI Key
Canonical SMILES	O/C(CC)=C(C#N)C(NC1=CC=C(C(F)(F)F)C=C1)=O

英文名	Leflunomide EP Impurity D
分子结构
CAS编号	42831-50-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-Methylisoxazole-4-carboxylic acid
分子式	C5H5NO3
分子量	127.1
InChI
InChI Key
Canonical SMILES	CC1=C(C(O)=O)C=NO1

英文名	Leflunomide EP Impurity E
分子结构
CAS编号	208401-20-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-Methyl-N-(4-(trifluoromethyl)phenyl)isoxazole-4-carboxamide
分子式	C12H9F3N2O2
分子量	270.2
InChI
InChI Key
Canonical SMILES	O=C(C1=CON=C1C)NC2=CC=C(C(F)(F)F)C=C2

英文名	Leflunomide EP Impurity C
分子结构
CAS编号	61643-23-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-Methyl-N-(3-(trifluoromethyl)phenyl)isoxazole-4-carboxamide
分子式	C12H9F3N2O2
分子量	270.2
InChI
InChI Key
Canonical SMILES	O=C(C1=C(C)ON=C1)NC2=CC=CC(C(F)(F)F)=C2