Leuprolide CAS#: 53714-56-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide
分子结构
CAS编号 53714-56-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-N-ethyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide
分子式 C59H84N16O12
分子量 1209.4
InChI
InChI Key
Canonical SMILES O=C(N[C@@H](CO)C(N[C@H](C(N[C@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N(CCC1)[C@@H]1C(NCC)=O)=O)=O)=O)=O)CC2=CC=C(O)C=C2)=O)[C@@H](NC([C@@H](NC([C@@H](N3)CCC3=O)=O)CC4=CNC=N4)=O)CC5=CNC6=C5C=CC=C6

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 944347-41-5 (mesylate salt) ; 74381-53-6 (Acetate salt)
Use Pattern
Leuprolide is chemically (S)-N-ethyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide. Leuprolide is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Impurity 4 CAS#: 267878-61-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Impurity 4
分子结构
CAS编号 267878-61-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-N-ethyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide
分子式 C56H79N15O10
分子量 1122.3
InChI
InChI Key
Canonical SMILES O=C(NCC)[C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CC(C)C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CNC=N5)NC([C@H](CC6)NC6=O)=O)=O)=O)=O)=O)=O)=O)CCC1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Impurity 4 is chemically (S)-N-ethyl-1-(((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide. Leuprolide Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Impurity 3 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Impurity 3
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-N-ethyl-1-(Nw-(2-hydroxyacetyl)-N2-((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
分子式 C61H86N16O14 : C2HF3O2
分子量 1267.5 : 114.0
InChI
InChI Key
Canonical SMILES O=C([C@H](CC1=CNC2=CC=CC=C21)NC([C@@H](NC([C@@H]3CCC(N3)=O)=O)CC4=CN=CN4)=O)N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N5CCC[C@H]5C(NCC)=O)=O)CCCNC(NC(CO)=O)=N)=O)CC(C)C)=O)CC(C)C)=O)CC6=CC=C(C=C6)O)=O)CO.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Impurity 3 is chemically (S)-N-ethyl-1-(Nw-(2-hydroxyacetyl)-N2-((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate. Leuprolide Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Des-Pyr-Leuprolide CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Des-Pyr-Leuprolide
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-1-(L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
分子式 C54H79N15O10 : C2HF3O2
分子量 1098.3 : 114.0
InChI
InChI Key
Canonical SMILES O=C(N[C@@H](CO)C(N[C@H](C(N[C@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N(CCC1)[C@@H]1C(NCC)=O)=O)=O)=O)=O)CC(C=C2)=CC=C2O)=O)[C@@H](NC([C@@H](N)CC3=CN=CN3)=O)CC4=CNC5=CC=CC=C45.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1642799-35-6 (free base)
Use Pattern
Des-Pyr-Leuprolide is chemically (S)-1-(L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate. Des-Pyr-Leuprolide is supplied with detailed characterization data compliant with regulatory guideline. Des-Pyr-Leuprolide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Des-1,2,3-Leuprolide Impurity CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Des-1,2,3-Leuprolide Impurity
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-1-(L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
分子式 C37H62N10O8 : C2HF3O2
分子量 775.0 : 114.0
InChI
InChI Key
Canonical SMILES N[C@H](C(N[C@H](C(N[C@@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(NCC)=O)=O)CCCNC(N)=N)=O)CC(C)C)=O)CC(C)C)=O)CC2=CC=C(C=C2)O)=O)CO.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 202333-85-5 (free base) ; 1620766-81-5 (dihydrochloride salt)
Use Pattern
Des-1,2,3-Leuprolide Impurity is chemically (S)-1-(L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate. Des-1,2,3-Leuprolide Impurity is supplied with detailed characterization data compliant with regulatory guideline. Des-1,2,3-Leuprolide Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Impurity 6 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Impurity 6
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 ((S)-5-Oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine compound with 2,2,2-trifluoroacetic acid (1:1)
分子式 C52H72N14O12 : C2HF3O2
分子量 1085.2 : 114.0
InChI
InChI Key
Canonical SMILES N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@@H](CC(C)C)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CO)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC4=CNC=N4)NC([C@H](CC5)NC5=O)=O)=O)=O)=O)=O)=O)=O.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 112642-14-5 (free base)
Use Pattern
Leuprolide Impurity 6 is chemically ((S)-5-Oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginine compound with 2,2,2-trifluoroacetic acid (1:1). Leuprolide Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Impurity 5 CAS#: 52434-75-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Impurity 5
分子结构
CAS编号 52434-75-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 ((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosine
分子式 C34H38N8O9
分子量 702.7
InChI
InChI Key
Canonical SMILES OC1=CC=C(C=C1)C[C@@H](C(O)=O)NC([C@H](CO)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CC4=CNC=N4)NC([C@H](CC5)NC5=O)=O)=O)=O)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Impurity 5 is chemically ((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosine. Leuprolide Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Impurity 2 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Impurity 2
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (2S)-N-ethyl-1-(Nw-(2-hydroxypropanoyl)-N2-((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
分子式 C62H88N16O14 : C2HF3O2
分子量 1281.5 : 114.0
InChI
InChI Key
Canonical SMILES O=C(N1)CC[C@H]1C(N[C@@](C(N[C@](CC2=CNC3=C2C=CC=C3)([H])C(N[C@](CO)([H])C(N[C@@]([H])(CC4=CC=C(O)C=C4)C(N[C@@](CC(C)C)([H])C(N[C@@]([H])(CC(C)C)C(N[C@](CCCNC(NC(C(O)C)=O)=N)([H])C(N5[C@@](C(NCC)=O)([H])CCC5)=O)=O)=O)=O)=O)=O)=O)([H])CC6=CN=CN6)=O.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Impurity 2 is chemically (2S)-N-ethyl-1-(Nw-(2-hydroxypropanoyl)-N2-((S)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide 2,2,2-trifluoroacetate. Leuprolide Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Acetate Impurity I CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Acetate Impurity I
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-N-Ethyl-1-(((R)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide di 2,2,2-trifluoroacetate
分子式 C59H84N16O12 : 2(C2HF3O2)
分子量 1209.4 : 2(114.0)
InChI
InChI Key
Canonical SMILES O=C([C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CC(C)C)NC([C@H](CC2=CC=C(O)C=C2)NC([C@H](CO)NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CN=CN5)NC([C@@H](CC6)NC6=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)NCC.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Acetate Impurity I is chemically (S)-N-Ethyl-1-(((R)-5-oxopyrrolidine-2-carbonyl)-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)pyrrolidine-2-carboxamide di 2,2,2-trifluoroacetate. Leuprolide Acetate Impurity I is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Acetate Impurity I can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Leuprolide Acetate Impurity K CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Leuprolide Acetate Impurity K
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-1-((2-((S)-2-((S)-3-(1H-imidazol-5-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanamido)-3-(1H-indol-3-yl)propanamido)acryloyl)-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate
分子式 C59H82N16O11 : C2HF3O2
分子量 1191.4 : 114.0
InChI
InChI Key
Canonical SMILES O=C([C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CC(C)C)NC([C@H](CC2=CC=C(O)C=C2)NC(C(NC([C@H](CC3=CNC4=C3C=CC=C4)NC([C@H](CC5=CN=CN5)NC([C@H](CC6)NC6=O)=O)=O)=O)=C)=O)=O)=O)=O)=O)CCC1)NCC.O=C(O)C(F)(F)F

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Leuprolide Acetate Impurity K is chemically (S)-1-((2-((S)-2-((S)-3-(1H-imidazol-5-yl)-2-((S)-5-oxopyrrolidine-2-carboxamido)propanamido)-3-(1H-indol-3-yl)propanamido)acryloyl)-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl)-N-ethylpyrrolidine-2-carboxamide 2,2,2-trifluoroacetate. Leuprolide Acetate Impurity K is supplied with detailed characterization data compliant with regulatory guideline. Leuprolide Acetate Impurity K can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Leuprolide. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.