Lifitegrast Impurity 15 CAS#: 2414639-05-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 15
分子结构
CAS编号 2414639-05-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 Tert-butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
分子式 C33H32Cl2N2O7S
分子量 671.6
InChI
InChI Key
Canonical SMILES ClC1=C(CCN2C(C3=CC=C4C(OC=C4)=C3)=O)C(C2)=CC(Cl)=C1C(N[C@H](C(OC(C)(C)C)=O)CC5=CC([S](C)(=O)=O)=CC=C5)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 15 is chemically Tert-butyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate. Lifitegrast Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 17 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 17
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid
分子式 C28H21BrCl2N2O5
分子量 616.3
InChI
InChI Key
Canonical SMILES O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(Br)=C5

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 17 is chemically (S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-bromophenyl)propanoic acid. Lifitegrast Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 16 CAS#: 2641788-18-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 16
分子结构
CAS编号 2641788-18-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
分子式 C39H35Cl2N3O10S2
分子量 840.7
InChI
InChI Key
Canonical SMILES O=C(O)[C@@H](NC([C@@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(S(=O)(C)=O)=C5)=O)CC6=CC=CC(S(=O)(C)=O)=C6

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 16 is chemically (S)-2-((S)-2-(2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid. Lifitegrast Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Ethyl Ester Impurity CAS#: 2295862-24-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Ethyl Ester Impurity
分子结构
CAS编号 2295862-24-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
分子式 C31H28Cl2N2O7S
分子量 643.5
InChI
InChI Key
Canonical SMILES ClC1=C2C(CN(CC2)C(C3=CC=C(C=CO4)C4=C3)=O)=CC(Cl)=C1C(N[C@H](C(OCC)=O)CC5=CC(S(C)(=O)=O)=CC=C5)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Ethyl Ester Impurity is chemically Ethyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate. Lifitegrast Ethyl Ester Impurity is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Ethyl Ester Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Benzyl Ester Impurity CAS#: 1194550-67-8

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Benzyl Ester Impurity
分子结构
CAS编号 1194550-67-8
EINECS Number
MDL Number
Beilstein Registry Number
别名 Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate
分子式 C36H30Cl2N2O7S
分子量 705.6
InChI
InChI Key
Canonical SMILES ClC1=C2C(CN(CC2)C(C3=CC=C(C=CO4)C4=C3)=O)=CC(Cl)=C1C(N[C@H](C(OCC5=CC=CC=C5)=O)CC6=CC(S(C)(=O)=O)=CC=C6)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Benzyl Ester Impurity is chemically Benzyl (S)-2-(2-(benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoate. Lifitegrast Benzyl Ester Impurity is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Benzyl Ester Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 18 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 18
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
分子式 C22H22Cl2N2O6S
分子量 513.4
InChI
InChI Key
Canonical SMILES O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CN(C(C)=O)CC2)C=C1Cl)=O)CC3=CC=CC(S(=O)(C)=O)=C3

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 18 is chemically (S)-2-(2-Acetyl-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid. Lifitegrast Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 12 CAS#: 77095-51-3

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 12
分子结构
CAS编号 77095-51-3
EINECS Number
MDL Number
Beilstein Registry Number
别名 Benzofuran-6-carboxylic acid
分子式 C9H6O3
分子量 162.1
InChI
InChI Key
Canonical SMILES OC(C1=CC=C2C(OC=C2)=C1)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 12 is chemically Benzofuran-6-carboxylic acid. Lifitegrast Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 11 CAS#: 2271054-95-4

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 11
分子结构
CAS编号 2271054-95-4
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid hydrochloride
分子式 C20H20Cl2N2O5S : HCl
分子量 471.3 : 36.5
InChI
InChI Key
Canonical SMILES O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CNCC2)C=C1Cl)=O)CC3=CC=CC(S(=O)(C)=O)=C3.Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 851785-70-1 (free base)
Use Pattern
Lifitegrast Impurity 11 is chemically (S)-2-(5,7-Dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid hydrochloride. Lifitegrast Impurity 11 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 11 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 14 CAS#: 2129597-34-6

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 14
分子结构
CAS编号 2129597-34-6
EINECS Number
MDL Number
Beilstein Registry Number
别名 2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid
分子式 C19H13Cl2NO4
分子量 390.2
InChI
InChI Key
Canonical SMILES ClC1=C(CCN2C(C3=CC=C4C(OC=C4)=C3)=O)C(C2)=CC(Cl)=C1C(O)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 14 is chemically 2-(Benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid. Lifitegrast Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lifitegrast Impurity 4 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lifitegrast Impurity 4
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (S)-2-(2-(benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid
分子式 C29H24BrClN2O7S
分子量 659.9
InChI
InChI Key
Canonical SMILES O=C(C1=C(Cl)C2=C(CN(C(C3=CC=C(C=CO4)C4=C3)=O)CC2)C=C1Br)N[C@@H](CC5=CC=CC(S(C)(=O)=O)=C5)C(O)=O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lifitegrast Impurity 4 is chemically (S)-2-(2-(benzofuran-6-carbonyl)-7-bromo-5-chloro-1,2,3,4-tetrahydroisoquinoline-6-carboxamido)-3-(3-(methylsulfonyl)phenyl)propanoic acid. Lifitegrast Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Lifitegrast Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lifitegrast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.