N-Nitroso Lorlatinib Impurity 2 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 N-Nitroso Lorlatinib Impurity 2
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)amino)methyl)-N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)nitrous amide
分子式 C43H37F2N13O5
分子量 853.9
InChI
InChI Key
Canonical SMILES FC1=CC=C(C(N(C)CC2=NN(C)C(C#N)=C2C3=CC4=C(N(N=O)CNC5=NC(C6=C(C#N)N(C)N=C6CN7C)=CC(O[C@H](C)C8=CC(F)=CC=C8C7=O)=C5)N=C3)=O)C([C@@H](C)O4)=C1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
N-Nitroso Lorlatinib Impurity 2 is chemically N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)amino)methyl)-N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)nitrous amide. N-Nitroso Lorlatinib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Lorlatinib impurity-4 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 N-Nitroso Lorlatinib impurity-4
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-2-(1-((2-Amino-5-(5-cyano-1-methyl-3-((methyl(nitroso)amino)methyl)-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acid
分子式 C21H20FN7O4
分子量 453.4
InChI
InChI Key
Canonical SMILES FC1=CC([C@@H](C)OC2=C(N)N=CC(C3=C(C#N)N(C)N=C3CN(N=O)C)=C2)=C(C(O)=O)C=C1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
N-Nitroso Lorlatinib impurity-4 is chemically (R)-2-(1-((2-Amino-5-(5-cyano-1-methyl-3-((methyl(nitroso)amino)methyl)-1H-pyrazol-4-yl)pyridin-3-yl)oxy)ethyl)-4-fluorobenzoic acid. N-Nitroso Lorlatinib impurity-4 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib impurity-4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Lorlatinib Impurity 1 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 N-Nitroso Lorlatinib Impurity 1
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)-N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)(nitroso)amino)methyl)nitrous amide
分子式 C43H36F2N14O6
分子量 882.8
InChI
InChI Key
Canonical SMILES FC1=CC=C(C(N(C)CC2=NN(C)C(C#N)=C2C3=CC4=C(N(N=O)CN(C5=NC(C6=C(C#N)N(C)N=C6CN7C)=CC(O[C@H](C)C8=CC(F)=CC=C8C7=O)=C5)N=O)N=C3)=O)C([C@@H](C)O4)=C1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
N-Nitroso Lorlatinib Impurity 1 is chemically N-((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(2,4)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)-N-((((R)-15-cyano-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-26-yl)(nitroso)amino)methyl)nitrous amide. N-Nitroso Lorlatinib Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Lorlatinib Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lorlatinib CAS#: 1454846-35-5

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lorlatinib
分子结构
CAS编号 1454846-35-5
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-26-amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile
分子式 C21H19FN6O2
分子量 406.4
InChI
InChI Key
Canonical SMILES N#CC(N1C)=C(C(CN(C(C2=CC=C(F)C=C32)=O)C)=N1)C4=CN=C(N)C(O[C@@H]3C)=C4

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Lorlatinib is chemically (R)-26-amino-55-fluoro-11,4,7-trimethyl-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile. Lorlatinib is supplied with detailed characterization data compliant with regulatory guideline. Lorlatinib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Lorlatinib 13CD3 CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Lorlatinib 13CD3
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (R)-26-amino-55-fluoro-11,4-dimethyl-7-(methyl-13C-d3)-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile
分子式 C2013CH16D3FN6O2
分子量 410.4
InChI
InChI Key
Canonical SMILES N#CC(N1C)=C(C(CN(C(C2=CC=C(F)C=C32)=O)[13C]([2H])([2H])[2H])=N1)C4=CN=C(N)C(O[C@@H]3C)=C4

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1454846-35-5 (Unlabelled)
Use Pattern
Lorlatinib 13CD3 is chemically (R)-26-amino-55-fluoro-11,4-dimethyl-7-(methyl-13C-d3)-6-oxo-11H-3-oxa-7-aza-2(3,5)-pyridina-1(4,3)-pyrazola-5(1,2)-benzenacyclooctaphane-15-carbonitrile. Lorlatinib 13CD3 is supplied with detailed characterization data compliant with regulatory guideline. Lorlatinib 13CD3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Lorlatinib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.