Macitentan • ChemWhat中文网 | 凯望化学与生物数据库

Macitentan Impurity 26 CAS#: 1516860-25-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 26 is chemically 5-(2-Bromophenyl)-4,6-dichloropyrimidine. Macitentan Impurity 26 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 26 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Macitentan Impurity 23 CAS#: 149506-35-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 23 is chemically Dimethyl 2-(4-bromophenyl)malonate. Macitentan Impurity 23 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 23 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Macitentan Impurity 28 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 28 is chemically . Macitentan Impurity 28 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 28 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Ethylene hydroxy Impurity CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Ethylene hydroxy Impurity is chemically . N-Nitroso Ethylene hydroxy Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Ethylene hydroxy Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Pyrimidine Amine Impurity CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Pyrimidine Amine Impurity is chemically . N-Nitroso Pyrimidine Amine Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Pyrimidine Amine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Macitentan Impurity 27 CAS#: 1532412-37-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 27 is chemically 5-(3-Bromophenyl)-4,6-dichloropyrimidine. Macitentan Impurity 27 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 27 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Macitentan Impurity 25 CAS#: 1393813-40-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 25 is chemically Tert-butyl (N-propylsulfamoyl)carbamate. Macitentan Impurity 25 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 25 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Macitentan CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Macitentan is chemically . N-Nitroso Macitentan is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Macitentan can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Macitentan Impurity 24 CAS#: 706811-25-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Macitentan Impurity 24 is chemically 5-(4-Bromophenyl)pyrimidine-4,6-diol. Macitentan Impurity 24 is supplied with detailed characterization data compliant with regulatory guideline. Macitentan Impurity 24 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Macitentan Dimer Impurity CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Macitentan Dimer Impurity is chemically . N-Nitroso Macitentan Dimer Impurity is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Macitentan Dimer Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Macitentan. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Macitentan Impurity 26
分子结构
CAS编号	1516860-25-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-(2-Bromophenyl)-4,6-dichloropyrimidine
分子式	C10H5BrCl2N2
分子量	304.0
InChI
InChI Key
Canonical SMILES	ClC1=NC=NC(Cl)=C1C(C=CC=C2)=C2Br

英文名	Macitentan Impurity 23
分子结构
CAS编号	149506-35-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	Dimethyl 2-(4-bromophenyl)malonate
分子式	C11H11BrO4
分子量	287.1
InChI
InChI Key
Canonical SMILES	O=C(OC)C(C(C=C1)=CC=C1Br)C(OC)=O

英文名	Macitentan Impurity 28
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式	C19H20BrClN6O4S
分子量	543.8
InChI
InChI Key
Canonical SMILES	BrC(C=C1)=CC=C1C2=C(NS(=O)(NCCC)=O)N=CN=C2OCCOC3=NC=C(Cl)C=N3

英文名	N-Nitroso Ethylene hydroxy Impurity
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式	C15H18BrN5O5S
分子量	460.3
InChI
InChI Key
Canonical SMILES	BrC1=CC=C(C2=C(NS(=O)(N(CCC)N=O)=O)N=CN=C2OCCO)C=C1

英文名	N-Nitroso Pyrimidine Amine Impurity
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式	C13H13BrClN5O3S
分子量	434.7
InChI
InChI Key
Canonical SMILES	BrC1=CC=C(C2=C(NS(=O)(N(CCC)N=O)=O)N=CN=C2Cl)C=C1

英文名	Macitentan Impurity 27
分子结构
CAS编号	1532412-37-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-(3-Bromophenyl)-4,6-dichloropyrimidine
分子式	C10H5BrCl2N2
分子量	304.0
InChI
InChI Key
Canonical SMILES	ClC1=NC=NC(Cl)=C1C2=CC(Br)=CC=C2

英文名	Macitentan Impurity 25
分子结构
CAS编号	1393813-40-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	Tert-butyl (N-propylsulfamoyl)carbamate
分子式	C8H18N2O4S
分子量	238.3
InChI
InChI Key
Canonical SMILES	O=[S](NC(OC(C)(C)C)=O)(NCCC)=O

英文名	N-Nitroso Macitentan
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式	C19H19Br2N7O5S
分子量	617.3
InChI
InChI Key
Canonical SMILES	BrC1=CC=C(C2=C(NS(=O)(N(CCC)N=O)=O)N=CN=C2OCCOC3=NC=C(Br)C=N3)C=C1

英文名	Macitentan Impurity 24
分子结构
CAS编号	706811-25-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	5-(4-Bromophenyl)pyrimidine-4,6-diol
分子式	C10H7BrN2O2
分子量	267.1
InChI
InChI Key
Canonical SMILES	OC1=NC=NC(O)=C1C2=CC=C(Br)C=C2

英文名	N-Nitroso Macitentan Dimer Impurity
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式	C28H30Br2N10O8S2
分子量	858.5
InChI
InChI Key
Canonical SMILES	BrC(C=C1)=CC=C1C2=C(NS(=O)(N(N=O)CCC)=O)N=CN=C2OCCOC3=C(C4=CC=C(Br)C=C4)C(NS(=O)(N(CCC)N=O)=O)=NC=N3