Nepafenac • ChemWhat中文网 | 凯望化学与生物数据库

Nepafenac Impurity 6 CAS#: 78281-75-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac Impurity 6 is chemically 2-(2-Amino-3-benzoylphenyl)-N-methylacetamide. Nepafenac Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity 5 CAS#: 78281-71-7

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac Impurity 5 is chemically 2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide. Nepafenac Impurity 5 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity 3 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	98790-48-8 (free base)

Use Pattern

Nepafenac Impurity 3 is chemically 2-Amino-3-benzoylbenzoic acid hydrochloride. Nepafenac Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity 4 CAS#: 91714-75-9

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	91714-74-8 (Na salt)

Use Pattern

Nepafenac Impurity 4 is chemically 2-(2-amino-3-benzoyl-5-methylphenyl)acetic acid. Nepafenac Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac CAS#: 78281-72-8

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac is chemically 2-(2-Amino-3-benzoylphenyl)acetamide. Nepafenac is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac D5 CAS#: 1246814-53-8

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac D5 is chemically 2-(2-Amino-3-(benzoyl-d5)phenyl)acetamide. Nepafenac D5 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity 1 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac Impurity 1 is chemically 2-(2-Amino-3-benzylphenyl)acetamide. Nepafenac Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity 2 CAS#: 61618-27-7

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	51579-82-9 (free base)

Use Pattern

Nepafenac Impurity 2 is chemically Sodium 2-(2-amino-3-benzoylphenyl)acetate hydrate. Nepafenac Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac USP Related Compound A CAS#: 1246956-18-2

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac USP Related Compound A is chemically 2-(2-Amino-3-(hydroxy(phenyl)methyl)phenyl)acetamide. Nepafenac USP Related Compound A is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac USP Related Compound A can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Nepafenac Impurity C CAS#: 2731586-58-4

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Nepafenac Impurity C is chemically 2-(2-Amino-3-benzoyl-6-chlorophenyl)acetamide. Nepafenac Impurity C is supplied with detailed characterization data compliant with regulatory guideline. Nepafenac Impurity C can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Nepafenac. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Nepafenac Impurity 6
分子结构
CAS编号	78281-75-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-benzoylphenyl)-N-methylacetamide
分子式	C16H16N2O2
分子量	268.3
InChI
InChI Key
Canonical SMILES	O=C(NC)CC1=CC=CC(C(C2=CC=CC=C2)=O)=C1N

英文名	Nepafenac Impurity 5
分子结构
CAS编号	78281-71-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-benzoyl-5-chlorophenyl)acetamide
分子式	C15H13ClN2O2
分子量	288.7
InChI
InChI Key
Canonical SMILES	NC(CC1=C(N)C(C(C2=CC=CC=C2)=O)=CC(Cl)=C1)=O

英文名	Nepafenac Impurity 3
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-Amino-3-benzoylbenzoic acid hydrochloride
分子式	C14H11NO3 : HCl
分子量	241.2 : 36.5
InChI
InChI Key
Canonical SMILES	OC(C1=C(N)C(C(C2=CC=CC=C2)=O)=CC=C1)=O.Cl

英文名	Nepafenac Impurity 4
分子结构
CAS编号	91714-75-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-amino-3-benzoyl-5-methylphenyl)acetic acid
分子式	C16H15NO3
分子量	269.3
InChI
InChI Key
Canonical SMILES	CC1=CC(C(C2=CC=CC=C2)=O)=C(N)C(CC(O)=O)=C1

英文名	Nepafenac
分子结构
CAS编号	78281-72-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-benzoylphenyl)acetamide
分子式	C15H14N2O2
分子量	254.3
InChI
InChI Key
Canonical SMILES	O=C(C1=CC=CC=C1)C(C=CC=C2CC(N)=O)=C2N

英文名	Nepafenac D5
分子结构
CAS编号	1246814-53-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-(benzoyl-d5)phenyl)acetamide
分子式	C15H9D5N2O2
分子量	259.3
InChI
InChI Key
Canonical SMILES	O=C(C(C([2H])=C1[2H])=C(C([2H])=C1[2H])[2H])C(C=CC=C2CC(N)=O)=C2N

英文名	Nepafenac Impurity 1
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-benzylphenyl)acetamide
分子式	C15H16N2O
分子量	240.3
InChI
InChI Key
Canonical SMILES	O=C(N)CC1=C(N)C(CC2=CC=CC=C2)=CC=C1

英文名	Nepafenac Impurity 2
分子结构
CAS编号	61618-27-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	Sodium 2-(2-amino-3-benzoylphenyl)acetate hydrate
分子式	C15H13NO3 : Na : H2O
分子量	254.3 : 23.0 : 18.0
InChI
InChI Key
Canonical SMILES	O=C(C1=C(N)C(CC([O-])=O)=CC=C1)C2=CC=CC=C2.[Na+].O

英文名	Nepafenac USP Related Compound A
分子结构
CAS编号	1246956-18-2
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-(hydroxy(phenyl)methyl)phenyl)acetamide
分子式	C15H16N2O2
分子量	256.3
InChI
InChI Key
Canonical SMILES	OC(C1=CC=CC(CC(N)=O)=C1N)C2=CC=CC=C2

英文名	Nepafenac Impurity C
分子结构
CAS编号	2731586-58-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(2-Amino-3-benzoyl-6-chlorophenyl)acetamide
分子式	C15H13ClN2O2
分子量	288.7
InChI
InChI Key
Canonical SMILES	O=C(C1=CC=C(Cl)C(CC(N)=O)=C1N)C2=CC=CC=C2