Pimavanserin • ChemWhat中文网 | 凯望化学与生物数据库

Di Vanillyl Amine Hydrochloride CAS#: 300346-57-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	16383-46-3 (free base)

Use Pattern

Di Vanillyl Amine Hydrochloride is chemically 4,4′-(Azanediylbis(methylene))bis(2-methoxyphenol) hydrochloride. Di Vanillyl Amine Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Di Vanillyl Amine Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Nitroso Desmethyl Pimavanserin CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso Desmethyl Pimavanserin is chemically 1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-nitrosopiperidin-4-yl)urea. N-Nitroso Desmethyl Pimavanserin is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso Desmethyl Pimavanserin can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Tartrate Impurity-F CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin Tartrate Impurity-F is chemically (2R,3R)-2,3-dihydroxy-4-((4-isobutoxybenzyl)amino)-4-oxobutanoic acid. Pimavanserin Tartrate Impurity-F is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Tartrate Impurity-F can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Sec-Butoxy Urea Impurity CAS#: 2377646-60-9

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin Sec-Butoxy Urea Impurity is chemically 3-(4-(sec-butoxy)benzyl)-1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)urea ; Urea, N-[(4-fluorophenyl)methyl]-N-(1-methyl]-4-piperidinyl)-N’-[[4-sec-butoxyphenyl]methyl]. Pimavanserin Sec-Butoxy Urea Impurity is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Sec-Butoxy Urea Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin N-Oxide CAS#: 1134815-71-6

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin N-Oxide is chemically 4-(1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)ureido)-1-methylpiperidine 1-oxide. Pimavanserin N-Oxide is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin N-Oxide can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Impurity 4 CAS#: 2512201-55-5

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin Impurity 4 is chemically 1-Benzyl-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea. Pimavanserin Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Impurity 6 CAS#: 2518374-84-8

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin Impurity 6 is chemically 1,1-Bis(4-fluorobenzyl)-3-(4-isobutoxybenzyl)urea. Pimavanserin Impurity 6 is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Impurity 6 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Isobutoxy Amine Impurity CAS#: 955997-89-4

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	4734-09-2 (free base)

Use Pattern

Pimavanserin Isobutoxy Amine Impurity is chemically (4-Isobutoxyphenyl)methanamine acetate ; 4-isobutoxybenzylammoniumacetate . Pimavanserin Isobutoxy Amine Impurity is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Isobutoxy Amine Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Tartrate CAS#: 706782-28-7

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	706779-91-1 (free base)

Use Pattern

Pimavanserin Tartrate is chemically 1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea (2R,3R)-2,3-dihydroxysuccinate. Pimavanserin Tartrate is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Tartrate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pimavanserin Impurity 21 CAS#: N/A

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Pimavanserin Impurity 21 is chemically 1-(4-isobutoxybenzyl)-3-(1-methylpiperidin-4-yl)urea. Pimavanserin Impurity 21 is supplied with detailed characterization data compliant with regulatory guideline. Pimavanserin Impurity 21 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pimavanserin. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Di Vanillyl Amine Hydrochloride
分子结构
CAS编号	300346-57-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	4,4′-(Azanediylbis(methylene))bis(2-methoxyphenol) hydrochloride
分子式	C16H19NO4 : HCl
分子量	289.3 : 36.5
InChI
InChI Key
Canonical SMILES	OC(C=C1)=C(OC)C=C1CNCC2=CC=C(O)C(OC)=C2.Cl

英文名	N-Nitroso Desmethyl Pimavanserin
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-nitrosopiperidin-4-yl)urea
分子式	C24H31FN4O3
分子量	442.5
InChI
InChI Key
Canonical SMILES	O=C(NCC1=CC=C(OCC(C)C)C=C1)N(C2CCN(N=O)CC2)CC3=CC=C(F)C=C3

英文名	Pimavanserin Tartrate Impurity-F
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	(2R,3R)-2,3-dihydroxy-4-((4-isobutoxybenzyl)amino)-4-oxobutanoic acid
分子式	C15H21NO6
分子量	311.3
InChI
InChI Key
Canonical SMILES	CC(C)COC1=CC=C(CNC([C@H](O)[C@@H](O)C(O)=O)=O)C=C1

英文名	Pimavanserin Sec-Butoxy Urea Impurity
分子结构
CAS编号	2377646-60-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-(4-(sec-butoxy)benzyl)-1-(4-fluorobenzyl)-1-(1-methylpiperidin-4-yl)urea ; Urea, N-[(4-fluorophenyl)methyl]-N-(1-methyl]-4-piperidinyl)-N’-[[4-sec-butoxyphenyl]methyl]
分子式	C25H34FN3O2
分子量	427.6
InChI
InChI Key
Canonical SMILES	CCC(C)OC1=CC=C(CNC(N(CC2=CC=C(F)C=C2)C3CCN(C)CC3)=O)C=C1

英文名	Pimavanserin N-Oxide
分子结构
CAS编号	1134815-71-6
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)ureido)-1-methylpiperidine 1-oxide
分子式	C25H34FN3O3
分子量	443.6
InChI
InChI Key
Canonical SMILES	FC(C=C1)=CC=C1CN(C2CC[N+](C)([O-])CC2)C(NCC3=CC=C(OCC(C)C)C=C3)=O

英文名	Pimavanserin Impurity 4
分子结构
CAS编号	2512201-55-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	1-Benzyl-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea
分子式	C25H35N3O2
分子量	409.6
InChI
InChI Key
Canonical SMILES	CC(C)COC(C=C1)=CC=C1CNC(N(C2CCN(C)CC2)CC3=CC=CC=C3)=O

英文名	Pimavanserin Impurity 6
分子结构
CAS编号	2518374-84-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	1,1-Bis(4-fluorobenzyl)-3-(4-isobutoxybenzyl)urea
分子式	C26H28F2N2O2
分子量	438.5
InChI
InChI Key
Canonical SMILES	CC(C)COC1=CC=C(CNC(N(CC2=CC=C(F)C=C2)CC3=CC=C(F)C=C3)=O)C=C1

英文名	Pimavanserin Isobutoxy Amine Impurity
分子结构
CAS编号	955997-89-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	(4-Isobutoxyphenyl)methanamine acetate ; 4-isobutoxybenzylammoniumacetate
分子式	C11H17NO : C2H4O2
分子量	179.3 : 60.1
InChI
InChI Key
Canonical SMILES	CC(C)COC1=CC=C(CN)C=C1.CC(O)=O

英文名	Pimavanserin Tartrate
分子结构
CAS编号	706782-28-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	1-(4-Fluorobenzyl)-3-(4-isobutoxybenzyl)-1-(1-methylpiperidin-4-yl)urea (2R,3R)-2,3-dihydroxysuccinate
分子式	C25H34FN3O2 : C4H4O6
分子量	427.6 : 148.1
InChI
InChI Key
Canonical SMILES	O=C(NCC1=CC=C(OCC(C)C)C=C1)N(C2CCN(C)CC2)CC3=CC=C(F)C=C3.OC([C@H](O)[C@@H](O)C(O)=O)=O

英文名	Pimavanserin Impurity 21
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	1-(4-isobutoxybenzyl)-3-(1-methylpiperidin-4-yl)urea
分子式	C18H29N3O2
分子量	319.5
InChI
InChI Key
Canonical SMILES	CN(CC1)CCC1NC(NCC2=CC=C(OCC(C)C)C=C2)=O