Pralatrexate Impurity 2 CAS#: 52454-37-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Pralatrexate Impurity 2
分子结构
CAS编号 52454-37-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-(2-(2,4-Diaminopteridin-6-yl)ethyl)benzoyl)-L-glutamic acid
分子式 C20H21N7O5
分子量 439.4
InChI
InChI Key
Canonical SMILES NC1=NC(N)=NC2=NC=C(CCC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)N=C12

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Pralatrexate Impurity 2 is chemically (4-(2-(2,4-Diaminopteridin-6-yl)ethyl)benzoyl)-L-glutamic acid. Pralatrexate Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Pralatrexate Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pralatrexate Impurity 3 CAS#: 309722-11-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Pralatrexate Impurity 3
分子结构
CAS编号 309722-11-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-(2-(2,4-Diaminopteridin-6-yl)ethyl)benzoyl)glutamic acid
分子式 C20H21N7O5
分子量 439.4
InChI
InChI Key
Canonical SMILES O=C(CCC(C(O)=O)NC(C1=CC=C(CCC2=CN=C(N=C(N)N=C3N)C3=N2)C=C1)=O)O

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Pralatrexate Impurity 3 is chemically (4-(2-(2,4-Diaminopteridin-6-yl)ethyl)benzoyl)glutamic acid. Pralatrexate Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Pralatrexate Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

R-Pralatrexate CAS#: 1320211-70-8

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 R-Pralatrexate
分子结构
CAS编号 1320211-70-8
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid
分子式 C23H23N7O5
分子量 477.5
InChI
InChI Key
Canonical SMILES NC1=NC2=C(C(N)=N1)N=C(C[C@@]([H])(CC#C)C3=CC=C(C(N[C@]([H])(C(O)=O)CCC(O)=O)=O)C=C3)C=N2

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 1320211-75-3 (HCl salt)
Use Pattern
R-Pralatrexate is chemically (4-((R)-1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid. R-Pralatrexate is supplied with detailed characterization data compliant with regulatory guideline. R-Pralatrexate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

10-Carbomethoxy Pralatrexate CAS#: N/A

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 10-Carbomethoxy Pralatrexate
分子结构
CAS编号 N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoyl)-L-glutamic acid
分子式 C25H25N7O7
分子量 535.5
InChI
InChI Key
Canonical SMILES NC1=C2C(N=CC(CC(C(OC)=O)(CC#C[H])C3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=N2)=NC(N)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
10-Carbomethoxy Pralatrexate is chemically (4-(2-((2,4-diaminopteridin-6-yl)methyl)-1-methoxy-1-oxopent-4-yn-2-yl)benzoyl)-L-glutamic acid. 10-Carbomethoxy Pralatrexate is supplied with detailed characterization data compliant with regulatory guideline. 10-Carbomethoxy Pralatrexate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Diethyl Ester D-Glutamic Acid Hydrochloride CAS#: 1001-19-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Diethyl Ester D-Glutamic Acid Hydrochloride
分子结构
CAS编号 1001-19-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 Diethyl D-glutamate hydrochloride
分子式 C9H17NO4 : HCl
分子量 203.2 : 36.5
InChI
InChI Key
Canonical SMILES N[C@@H](C(OCC)=O)CCC(OCC)=O.Cl

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals 13107-55-6 (free base)
Use Pattern
Diethyl Ester D-Glutamic Acid Hydrochloride is chemically Diethyl D-glutamate hydrochloride. Diethyl Ester D-Glutamic Acid Hydrochloride is supplied with detailed characterization data compliant with regulatory guideline. Diethyl Ester D-Glutamic Acid Hydrochloride can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

4-(4-Hydroxy-1-Butynyl)Benzoic Acid Methyl Ester CAS#: 123910-86-1

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 4-(4-Hydroxy-1-Butynyl)Benzoic Acid Methyl Ester
分子结构
CAS编号 123910-86-1
EINECS Number
MDL Number
Beilstein Registry Number
别名 Methyl 4-(4-hydroxybut-1-yn-1-yl)benzoate
分子式 C12H12O3
分子量 204.2
InChI
InChI Key
Canonical SMILES O=C(C1=CC=C(C#CCCO)C=C1)OC

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
4-(4-Hydroxy-1-Butynyl)Benzoic Acid Methyl Ester is chemically Methyl 4-(4-hydroxybut-1-yn-1-yl)benzoate. 4-(4-Hydroxy-1-Butynyl)Benzoic Acid Methyl Ester is supplied with detailed characterization data compliant with regulatory guideline. 4-(4-Hydroxy-1-Butynyl)Benzoic Acid Methyl Ester can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pralatrexate Impurity 1 CAS#: 374777-77-2

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Pralatrexate Impurity 1
分子结构
CAS编号 374777-77-2
EINECS Number
MDL Number
Beilstein Registry Number
别名 Dimethyl (4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamate
分子式 C25H27N7O5
分子量 505.5
InChI
InChI Key
Canonical SMILES NC1=C2C(N=CC(CC(CC#C[H])C3=CC=C(C(N[C@@H](CCC(OC)=O)C(OC)=O)=O)C=C3)=N2)=NC(N)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Pralatrexate Impurity 1 is chemically Dimethyl (4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamate. Pralatrexate Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Pralatrexate Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Pralatrexate R-Isomer CAS#: 1451250-74-0

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Pralatrexate R-Isomer
分子结构
CAS编号 1451250-74-0
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-D-glutamic acid
分子式 C23H23N7O5
分子量 477.5
InChI
InChI Key
Canonical SMILES NC1=C2C(N=CC(CC([H])(CC#C)C3=CC=C(C(N[C@H](CCC(O)=O)C(O)=O)=O)C=C3)=N2)=NC(N)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Pralatrexate R-Isomer is chemically (4-(1-(2,4-diaminopteridin-6-yl)pent-4-yn-2-yl)benzoyl)-D-glutamic acid. Pralatrexate R-Isomer is supplied with detailed characterization data compliant with regulatory guideline. Pralatrexate R-Isomer can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Des-Glu-Pralatrexate CAS#: 146464-93-9

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 Des-Glu-Pralatrexate
分子结构
CAS编号 146464-93-9
EINECS Number
MDL Number
Beilstein Registry Number
别名 10-Propargyl-4-deoxy-4-amino-10-deazapteroic Acid
分子式 C18H16N6O2
分子量 348.4
InChI
InChI Key
Canonical SMILES NC1=C2C(N=CC(CC([H])(CC#C[H])C3=CC=C(C(O)=O)C=C3)=N2)=NC(N)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
Des-Glu-Pralatrexate is chemically 10-Propargyl-4-deoxy-4-amino-10-deazapteroic Acid. Des-Glu-Pralatrexate is supplied with detailed characterization data compliant with regulatory guideline. Des-Glu-Pralatrexate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

4-Hydroxy Pralatrexate CAS#: 1548618-61-6

By great_watson-int,
Identification Physical Data Spectra
Route of Synthesis (ROS) Safety and Hazards Other Data

Identification

英文名 4-Hydroxy Pralatrexate
分子结构
CAS编号 1548618-61-6
EINECS Number
MDL Number
Beilstein Registry Number
别名 (4-(1-(2-amino-4-hydroxypteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid
分子式 C23H22N6O6
分子量 478.5
InChI
InChI Key
Canonical SMILES OC1=C2C(N=CC(CC([H])(CC#C[H])C3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)C=C3)=N2)=NC(N)=N1

Physical Data

Appearance No data available
Solubility No data available
Flash Point No data available
Refractive index No data available
Sensitivity No data available
Melting Point No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code 382290
Storage At room temperature and away from light
Related Chemicals
Use Pattern
4-Hydroxy Pralatrexate is chemically (4-(1-(2-amino-4-hydroxypteridin-6-yl)pent-4-yn-2-yl)benzoyl)-L-glutamic acid. 4-Hydroxy Pralatrexate is supplied with detailed characterization data compliant with regulatory guideline. 4-Hydroxy Pralatrexate can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pralatrexate. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.