Roflumilast • ChemWhat中文网 | 凯望化学与生物数据库

Roflumilast Impurity 20 CAS#: 151103-09-2

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 20 is chemically 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde. Roflumilast Impurity 20 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 20 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 18 CAS#: 162401-60-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 18 is chemically 3,4-Bis(difluoromethoxy)benzoic acid. Roflumilast Impurity 18 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 18 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 17 CAS#: 2376345-94-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 17 is chemically 3-Cyclobutoxy-4-(difluoromethoxy)benzoic acid. Roflumilast Impurity 17 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 17 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 21 CAS#: 1369851-30-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 21 is chemically 3,4-Bis(cyclopropylmethoxy)benzoic acid. Roflumilast Impurity 21 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 21 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 19 CAS#: 25934-52-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 19 is chemically 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde. Roflumilast Impurity 19 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 19 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 14 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 14 is chemically 1,2-Bis(3-chloropyridin-4-yl)diazene. Roflumilast Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 16 CAS#: 162401-30-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 16 is chemically N-(3,5-Dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide. Roflumilast Impurity 16 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 16 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 13 CAS#: 1882067-44-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 13 is chemically 3-(But-3-en-1-yloxy)-4-(difluoromethoxy)benzoic acid. Roflumilast Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 15 CAS#: 127842-54-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 15 is chemically 3,4-Bis(difluoromethoxy)benzaldehyde. Roflumilast Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roflumilast Impurity 12 CAS#: 162401-43-6

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roflumilast Impurity 12 is chemically 4-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-3-(difluoromethoxy)benzamide. Roflumilast Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Roflumilast Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roflumilast. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Roflumilast Impurity 20
分子结构
CAS编号	151103-09-2
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde
分子式	C12H12F2O3
分子量	242.2
InChI
InChI Key
Canonical SMILES	O=CC1=CC=C(OC(F)F)C(OCC2CC2)=C1

英文名	Roflumilast Impurity 18
分子结构
CAS编号	162401-60-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	3,4-Bis(difluoromethoxy)benzoic acid
分子式	C9H6F4O4
分子量	254.1
InChI
InChI Key
Canonical SMILES	O=C(O)C1=CC(OC(F)F)=C(OC(F)F)C=C1

英文名	Roflumilast Impurity 17
分子结构
CAS编号	2376345-94-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-Cyclobutoxy-4-(difluoromethoxy)benzoic acid
分子式	C12H12F2O4
分子量	258.2
InChI
InChI Key
Canonical SMILES	FC(F)OC(C=C1)=C(C=C1C(O)=O)OC2CCC2

英文名	Roflumilast Impurity 21
分子结构
CAS编号	1369851-30-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	3,4-Bis(cyclopropylmethoxy)benzoic acid
分子式	C15H18O4
分子量	262.3
InChI
InChI Key
Canonical SMILES	O=C(O)C1=CC=C(OCC2CC2)C(OCC3CC3)=C1

英文名	Roflumilast Impurity 19
分子结构
CAS编号	25934-52-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
分子式	C11H12O3
分子量	192.2
InChI
InChI Key
Canonical SMILES	O=CC1=CC=C(O)C(OCC2CC2)=C1

英文名	Roflumilast Impurity 14
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	1,2-Bis(3-chloropyridin-4-yl)diazene
分子式	C10H6Cl2N4
分子量	253.1
InChI
InChI Key
Canonical SMILES	ClC1=CN=CC=C1N=NC2=CC=NC=C2Cl

英文名	Roflumilast Impurity 16
分子结构
CAS编号	162401-30-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(3,5-Dichloropyridin-4-yl)-3,4-bis(difluoromethoxy)benzamide
分子式	C14H8Cl2F4N2O3
分子量	399.1
InChI
InChI Key
Canonical SMILES	FC(F)OC(C=C(C(NC(C(Cl)=CN=C1)=C1Cl)=O)C=C2)=C2OC(F)F

英文名	Roflumilast Impurity 13
分子结构
CAS编号	1882067-44-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	3-(But-3-en-1-yloxy)-4-(difluoromethoxy)benzoic acid
分子式	C12H12F2O4
分子量	258.2
InChI
InChI Key
Canonical SMILES	O=C(O)C1=CC=C(OC(F)F)C(OCCC=C)=C1

英文名	Roflumilast Impurity 15
分子结构
CAS编号	127842-54-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	3,4-Bis(difluoromethoxy)benzaldehyde
分子式	C9H6F4O3
分子量	238.1
InChI
InChI Key
Canonical SMILES	FC(F)OC1=CC=C(C=O)C=C1OC(F)F

英文名	Roflumilast Impurity 12
分子结构
CAS编号	162401-43-6
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-3-(difluoromethoxy)benzamide
分子式	C17H14Cl2F2N2O3
分子量	403.2
InChI
InChI Key
Canonical SMILES	FC(F)OC(C=C(C(NC(C(Cl)=CN=C1)=C1Cl)=O)C=C2)=C2OCC3CC3