Roxadustat • ChemWhat中文网 | 凯望化学与生物数据库

Roxadustat Impurity 13 CAS#: 1809286-36-9

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	2342600-66-0 (HCl salt) ; 2342600-68-2 (hemisulfate salt)

Use Pattern

Roxadustat Impurity 13 is chemically Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate. Roxadustat Impurity 13 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 13 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat-D5 CAS#: 2043026-13-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat-D5 is chemically (4-Hydroxy-1-methyl-7-(phenoxy-d5)isoquinoline-3-carbonyl)glycine. Roxadustat-D5 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat-D5 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 12 CAS#: 1421312-35-7

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 12 is chemically 4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid. Roxadustat Impurity 12 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 12 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 15 CAS#: 2222121-33-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 15 is chemically Ethyl 5-(2-bromo-4-phenoxyphenyl)oxazole-4-carboxylate. Roxadustat Impurity 15 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 15 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 9 CAS#: 37951-15-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 9 is chemically 4-Phenoxyphthalic acid. Roxadustat Impurity 9 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 9 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 11 CAS#: 1421312-34-6

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 11 is chemically Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate. Roxadustat Impurity 11 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 11 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 14 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 14 is chemically 4-Hydroxy-1-methyl-N-(3-(2-oxoazepan-1-yl)propyl)-7-phenoxyisoquinoline-3-carboxamide. Roxadustat Impurity 14 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 14 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Methyl Ester Impurity CAS#: 1421312-36-8

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Methyl Ester Impurity is chemically Methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate. Roxadustat Methyl Ester Impurity is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Methyl Ester Impurity can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 8 CAS#: 2244489-54-9

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 8 is chemically Ethyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate. Roxadustat Impurity 8 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 8 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Roxadustat Impurity 7 CAS#: 2342600-59-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Roxadustat Impurity 7 is chemically 2-(Butoxycarbonyl)-4-phenoxybenzoic acid. Roxadustat Impurity 7 is supplied with detailed characterization data compliant with regulatory guideline. Roxadustat Impurity 7 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Roxadustat. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	Roxadustat Impurity 13
分子结构
CAS编号	1809286-36-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	Ethyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
分子式	C19H17NO4
分子量	323.3
InChI
InChI Key
Canonical SMILES	O=C(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)OCC

英文名	Roxadustat-D5
分子结构
CAS编号	2043026-13-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	(4-Hydroxy-1-methyl-7-(phenoxy-d5)isoquinoline-3-carbonyl)glycine
分子式	C19H11D5N2O5
分子量	357.4
InChI
InChI Key
Canonical SMILES	CC(C1=C2C=CC(OC3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])=C1)=NC(C(NCC(O)=O)=O)=C2O

英文名	Roxadustat Impurity 12
分子结构
CAS编号	1421312-35-7
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-Hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylic acid
分子式	C17H13NO4
分子量	295.3
InChI
InChI Key
Canonical SMILES	O=C(C1=C(O)C2=C(C=C(C=C2)OC3=CC=CC=C3)C(C)=N1)O

英文名	Roxadustat Impurity 15
分子结构
CAS编号	2222121-33-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	Ethyl 5-(2-bromo-4-phenoxyphenyl)oxazole-4-carboxylate
分子式	C18H14BrNO4
分子量	388.2
InChI
InChI Key
Canonical SMILES	O=C(C1=C(C2=CC=C(OC3=CC=CC=C3)C=C2Br)OC=N1)OCC

英文名	Roxadustat Impurity 9
分子结构
CAS编号	37951-15-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-Phenoxyphthalic acid
分子式	C14H10O5
分子量	258.2
InChI
InChI Key
Canonical SMILES	OC(C(C=C1OC2=CC=CC=C2)=C(C=C1)C(O)=O)=O

英文名	Roxadustat Impurity 11
分子结构
CAS编号	1421312-34-6
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl 4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carboxylate
分子式	C18H15NO4
分子量	309.3
InChI
InChI Key
Canonical SMILES	O=C(C1=C(O)C2=C(C=C(C=C2)OC3=CC=CC=C3)C(C)=N1)OC

英文名	Roxadustat Impurity 14
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-Hydroxy-1-methyl-N-(3-(2-oxoazepan-1-yl)propyl)-7-phenoxyisoquinoline-3-carboxamide
分子式	C26H29N3O4
分子量	447.5
InChI
InChI Key
Canonical SMILES	O=C(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)NCCCN4C(CCCCC4)=O

英文名	Roxadustat Methyl Ester Impurity
分子结构
CAS编号	1421312-36-8
EINECS Number
MDL Number
Beilstein Registry Number
别名	Methyl (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycinate
分子式	C20H18N2O5
分子量	366.4
InChI
InChI Key
Canonical SMILES	O=C(OC)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O

英文名	Roxadustat Impurity 8
分子结构
CAS编号	2244489-54-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	Ethyl 4-hydroxy-1-oxo-7-phenoxy-1,2-dihydroisoquinoline-3-carboxylate
分子式	C18H15NO5
分子量	325.3
InChI
InChI Key
Canonical SMILES	O=C(N1)C2=CC(OC3=CC=CC=C3)=CC=C2C(O)=C1C(OCC)=O

英文名	Roxadustat Impurity 7
分子结构
CAS编号	2342600-59-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	2-(Butoxycarbonyl)-4-phenoxybenzoic acid
分子式	C18H18O5
分子量	314.3
InChI
InChI Key
Canonical SMILES	O=C(O)C1=CC=C(C=C1C(OCCCC)=O)OC2=CC=CC=C2