Levothyroxine EP Impurity B CAS#: 76353-71-41

By great_watson-int,
IdentificationPhysical DataSpectra
Route of Synthesis (ROS)Safety and HazardsOther Data

Identification

英文名Levothyroxine EP Impurity B
分子结构
CAS编号 76353-71-41
EINECS Number
MDL Number
Beilstein Registry Number
别名
分子式C15H11ClI3NO4
分子量685.42
InChI
InChI Key
Canonical SMILES

Physical Data

Appearance
Solubility
Flash PointNo data available
Refractive indexNo data available
SensitivityNo data available
Melting PointNo data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

Use Pattern
Levothyroxine EP Impurity B is an impurity of API Thyroxine.

Anti-T4 (thyroxine T4 CAS#: 51-48-9) Antibody

By great_watson-int,
Thyroxine T4 Antibody in ELISA
AntigenDescriptionProperties
Safety InformationImagesOther Info

Antigen

NameThyroxine T4
别名T4; Thyroxine; 51-48-9;

Description

NameAnti-Thyroxine (T4) Antibody
别名Anti-T4 Antibody; Anti-Thyroxine antibody; L-Thyroxine (T4) antibody
HostMouse; Goat; Rabbit
ReactivityAll species
Antibody Product Type  Primary
Conjugate Unconjugated; Biotin; APC; Alkaline Phosphatase (AP); FITC; HRP; PE
SpecifityRecognizes Thyroxine, also known as T4, the major hormone secreted by the follicular cells of the thyroid gland. Its main role is to regulate metabolic processes in the body such as heart rate, along with Triiodothyronine (T3). T4 is involved in thyroid disorders, such as hyperthyroidism and hypothyroidism. 
ApplicationELISA; Immunohistochemistry (IHC); Western Blotting (WB); Immunofluorescence (fixed cells) (IF/ICC); Immunoprecipitation (IP); Cell-ELISA (cELISA); Immunoassay (IA); Immunocytochemistry (ICC)

Properties

FormLiquid/Lyophilized
HandlingThe antibody solution should be gently mixed before use.
Storage ConditionStore at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for a year without detectable loss of activity. Avoid repeated freeze-thaw cycles.
ClonalityMonoclonal/Polyclonal
IsotypeIgG

Safety Information

RIDADRNONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable

Images

Thyroxine T4 Antibody in ELISAThyroxine T4 Antibody in ELISA
Thyroxine T4 Antibody in WBThyroxine T4 Antibody in WB

Other Info

About the antigenAntibodies against thyroxine (T4) were detected in a patient of systemic lupus erythematosus associated with chronic thyroiditis and a patient with primary myxedema. Both patients were clincally hypothyroid with elevated serum TSH. Serum T4 values measured with solid phase radioimmunoassay were very high (over 25ug/dl), but were undetected with polyethylene glycol separation method. On the extraction of the sera with ethanol, the concordant low values of T4 were obtained with both radioimmunoassay methods and these values were compatible with clinical findings and serum TSH levels. The thyroid hormones, thyroxine (T4) and triiodothyronine (T3), are tyrosine-based hormones produced by the thyroid gland primarily responsible for regulation of metabolism. An important component in the synthesis of thyroid hormones is iodine. The major form of thyroid hormone in the blood is thyroxine (T4), which has a longer half life than T3.

L-Thyroxine CAS#: 51-48-9

By great_watson-int,

Names & Identifiers
英文名 L-Thyroxine
别名 3,5,3’,5’-tetraiodothyronine;beta-[(3,5-diiodo-4-hydroxyphenoxy)-3,5-diiodophenyl]alanine;l-3,5,3’,5’-tetraiodothyronine;l-t4;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodo-l-tyrosin;o-(4-hydroxy-3,5-diiodophenyl)-3,5-diiodotyrosine;t4(hormone);tetraiodothyronine
CAS编号 51-48-9
分子式 C15H11I4NO4
分子量 776.87
EINECS 200-101-1
Other Registry Numbers
More Identifiers on PubChem IUPA Names, InChI, InChI Key, Canonical SMILES, etc.
L-Thyroxine CAS#: 51-48-9

Chemical & Physical Properties
Melting point  235 °C
alpha  -5 º (1N NaOH:EtOH 1:2)
Flash Point  9℃
Storage  2-8°C
Solubulity  Dissolves in 4M ammonium hydroxide in Methanol at 50mg/ml
pka 2.2(at 25℃)
form  Powder
Color  White to Pale Brown
Water Solubility  insoluble
Sensitive  Light Sensitive
Merck  9491
InChIKey XUIIKFGFIJCVMT-LBPRGKRZSA-N
More Properties From PubChem Topological Polar Surface Area, Monoisotopic Mass, etc.
EPA Substance Registry System L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-(51-48-9)

Safety & Hazards(Codes & Phrases)
Hazard Codes  Xn,T,F
R Phrase  40-39/23/24/25-23/24/25-11
S Phrase  22-24/25-36-45-36/37-16
RIDADR  UN1230 – class 3 – PG 2 – Methanol, solution
WGK Germany  3
RTECS  YP2833500
F  8-10
TSCA  Yes
Storage Class  IRRITANT
Hazardous Substances Data 51-48-9(Hazardous Substances Data)
More Safety & Hazards From PubChem Signal, GHS Hazard Statements, Precautionary Statement Codes, etc.

Literature
Literature on PubChem Synthesis References, Metabolite References, etc.

Patents
Patents on PubChem Related Patents Of This Product

Transportation, Storage & Usage
Transportation No Information
Storage No Information
Usage No Information

Spectral Properties
No Information