Vandetanib • ChemWhat中文网 | 凯望化学与生物数据库

N-Nitroso N-Desmethyl Vandetanib CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Nitroso N-Desmethyl Vandetanib is chemically N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-nitrosopiperidin-4-yl)methoxy)quinazolin-4-amine. N-Nitroso N-Desmethyl Vandetanib is supplied with detailed characterization data compliant with regulatory guideline. N-Nitroso N-Desmethyl Vandetanib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib Impurity 2 CAS#: 196603-96-0

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	932016-10-9 (HCl salt) ; 2365040-91-9 (sodium salt) ; 2365040-92-0 (potassium salt) ; 932016-08-5 (TFA salt)

Use Pattern

Vandetanib Impurity 2 is chemically 4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol. Vandetanib Impurity 2 is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib Impurity 2 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib Impurity 4 CAS#: 162364-72-9

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	193001-44-4 (HCl salt)

Use Pattern

Vandetanib Impurity 4 is chemically 7-(Benzyloxy)-4-chloro-6-methoxyquinazoline. Vandetanib Impurity 4 is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib Impurity 4 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

N-Desmethyl Vandetanib CAS#: 338992-12-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

N-Desmethyl Vandetanib is chemically N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine. N-Desmethyl Vandetanib is supplied with detailed characterization data compliant with regulatory guideline. N-Desmethyl Vandetanib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib Impurity 3 CAS#: 768350-54-5

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals	196603-95-9 (HCl salt)

Use Pattern

Vandetanib Impurity 3 is chemically 7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine. Vandetanib Impurity 3 is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib Impurity 3 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib Impurity 1 CAS#: 338992-20-4

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Vandetanib Impurity 1 is chemically Tert-butyl 4-(((4-((4-bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate. Vandetanib Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

O-Desmethyl Vandetanib CAS#: 910298-60-1

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

O-Desmethyl Vandetanib is chemically 4-((4-Bromo-2-fluorophenyl)amino)-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-6-ol. O-Desmethyl Vandetanib is supplied with detailed characterization data compliant with regulatory guideline. O-Desmethyl Vandetanib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Pharmaceutical Reference Standards. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib Nitroso Impurity 1 CAS#: N/A

By great_watson-int, 7th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Vandetanib Nitroso Impurity 1 is chemically N-(4-Bromo-2-fluorophenyl)-N-(6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-yl)nitrous amide. Vandetanib Nitroso Impurity 1 is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib Nitroso Impurity 1 can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

Vandetanib CAS#: 443913-73-3

By great_watson-int, 6th July 2024

Identification	Physical Data	Spectra
Route of Synthesis (ROS)	Safety and Hazards	Other Data

Identification

Physical Data

Appearance	No data available
Solubility	No data available
Flash Point	No data available
Refractive index	No data available
Sensitivity	No data available
Melting Point	No data available

Spectra

No data available

Route of Synthesis (ROS)

No data available

Safety and Hazards

No data available

Other Data

HS Code	382290
Storage	At room temperature and away from light
Related Chemicals

Use Pattern

Vandetanib is chemically 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline. Vandetanib is supplied with detailed characterization data compliant with regulatory guideline. Vandetanib can be used for the analytical method development, method validation (AMV), Quality Controlled (QC) application for Abbreviated New Drug Application (ANDA) or during commercial production of Vandetanib. The product can be used as reference standards and further traceability against pharmacopeial standards (USP or EP) can be provided based on feasibility. ChemWhat products are for analytical purpose only and not for human use.

英文名	N-Nitroso N-Desmethyl Vandetanib
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-((1-nitrosopiperidin-4-yl)methoxy)quinazolin-4-amine
分子式	C21H21BrFN5O3
分子量	490.3
InChI
InChI Key
Canonical SMILES	O=NN1CCC(COC2=CC3=NC=NC(NC4=CC=C(Br)C=C4F)=C3C=C2OC)CC1

英文名	Vandetanib Impurity 2
分子结构
CAS编号	196603-96-0
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-((4-Bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-ol
分子式	C15H11BrFN3O2
分子量	364.2
InChI
InChI Key
Canonical SMILES	COC1=CC(C(NC(C=CC(Br)=C2)=C2F)=NC=N3)=C3C=C1O

英文名	Vandetanib Impurity 4
分子结构
CAS编号	162364-72-9
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-(Benzyloxy)-4-chloro-6-methoxyquinazoline
分子式	C16H13ClN2O2
分子量	300.7
InChI
InChI Key
Canonical SMILES	ClC1=NC=NC(C=C2OCC3=CC=CC=C3)=C1C=C2OC

英文名	N-Desmethyl Vandetanib
分子结构
CAS编号	338992-12-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine
分子式	C21H22BrFN4O2
分子量	461.3
InChI
InChI Key
Canonical SMILES	COC1=CC(C(NC(C=CC(Br)=C2)=C2F)=NC=N3)=C3C=C1OCC4CCNCC4

英文名	Vandetanib Impurity 3
分子结构
CAS编号	768350-54-5
EINECS Number
MDL Number
Beilstein Registry Number
别名	7-(Benzyloxy)-N-(4-bromo-2-fluorophenyl)-6-methoxyquinazolin-4-amine
分子式	C22H17BrFN3O2
分子量	454.3
InChI
InChI Key
Canonical SMILES	COC1=CC(C(NC(C=CC(Br)=C2)=C2F)=NC=N3)=C3C=C1OCC4=CC=CC=C4

英文名	Vandetanib Impurity 1
分子结构
CAS编号	338992-20-4
EINECS Number
MDL Number
Beilstein Registry Number
别名	Tert-butyl 4-(((4-((4-bromo-2-fluorophenyl)amino)-6-methoxyquinazolin-7-yl)oxy)methyl)piperidine-1-carboxylate
分子式	C26H30BrFN4O4
分子量	561.5
InChI
InChI Key
Canonical SMILES	COC1=CC(C(NC(C=CC(Br)=C2)=C2F)=NC=N3)=C3C=C1OCC(CC4)CCN4C(OC(C)(C)C)=O

英文名	O-Desmethyl Vandetanib
分子结构
CAS编号	910298-60-1
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-((4-Bromo-2-fluorophenyl)amino)-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-6-ol
分子式	C21H22BrFN4O2
分子量	461.3
InChI
InChI Key
Canonical SMILES	FC1=C(C=CC(Br)=C1)NC2=NC=NC3=C2C=C(O)C(OCC4CCN(C)CC4)=C3

英文名	Vandetanib Nitroso Impurity 1
分子结构
CAS编号	N/A
EINECS Number
MDL Number
Beilstein Registry Number
别名	N-(4-Bromo-2-fluorophenyl)-N-(6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-yl)nitrous amide
分子式	C22H23BrFN5O3
分子量	504.4
InChI
InChI Key
Canonical SMILES	CN1CCC(COC2=CC3=NC=NC(N(N=O)C4=CC=C(Br)C=C4F)=C3C=C2OC)CC1

英文名	Vandetanib
分子结构
CAS编号	443913-73-3
EINECS Number
MDL Number
Beilstein Registry Number
别名	4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline
分子式	C22H24BrFN4O2
分子量	475.4
InChI
InChI Key
Canonical SMILES	CN1CCC(COC2=CC3=NC=NC(NC4=CC=C(Br)C=C4F)=C3C=C2OC)CC1