| 英文名 |
11-cis-retinol dehydrogenase |
| Example Structure |
 |
| 别名 |
isethionate formation, reductase D, IsfD, IsfD2, NADPH-dependent sulfoacetaldehyde reductase |
| EC Number |
1.1.1.315 |
| CAS编号 |
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| Comments |
This enzyme, abundant in the retinal pigment epithelium, catalyses the reduction of 11-cis-retinol to 11-cis-retinal [1] while the substrate is bound to the retinal-binding protein [4]. This is a crucial step in the regeneration of 11-cis-retinal, the chromophore of rhodopsin. The enzyme can also accept other cis forms of retinol [2]. |
| Cofactor |
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| History |
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| Reactions |
11-cis-retinol-[retinal-binding-protein] + NAD(+) = 11-cis-retinal- [retinol-binding-protein] + Nadh. |
