| 英文名 |
2-acyl-4-prenylphloroglucinol 6-prenyltransferase |
| Example Structure |
 |
| 别名 |
aromatic prenyltransferase, PT2 |
| EC Number |
2.5.1.137 |
| CAS编号 |
|
| Comments |
The enzyme, characterized from hop (Humulus lupulus), catalyses two successive prenylations of a 2-acyl-4-prenylphloroglucinol during the synthesis of bitter acids. Forms a complex with EC 2.5.1.136, 2-acylphloroglucinol 4-prenyltransferase, which catalyses the initial prenylation of the substrates. Requires Mg2+. |
| Cofactor |
Mg2+ |
| History |
|
| Reactions |
(1) Dimethylallyl diphosphate + a 2-acyl-4-prenylphloroglucinol = diphosphate + a 2-acyl-4,6-bisprenylphloroglucinol. (2) Dimethylallyl diphosphate + a 2-acyl-4,6-bisprenylphloroglucinol = diphosphate + a 2-acyl-4,6,6-trisprenylphloroglucinol. |