2-aminophenol 1,6-dioxygenase EC#: 1.13.11.74; 凯望编码 (ChemWhat Code): 1375005

英文名 2-aminophenol 1,6-dioxygenase
Example Structure Example Structure of 2-aminophenol 1,6-dioxygenase EC#: 1.13.11.74
别名 amnA, amnB, amnBA, APD
EC Number 1.13.11.74
CAS编号
Comments The enzyme, a member of the nonheme-iron(II)-dependent dioxygenase family, is an extradiol-type dioxygenase that utilizes a non-heme ferrous iron to cleave the aromatic ring at the meta position (relative to the hydroxyl substituent). The enzyme also has some activity with 2-amino-5-methylphenol and 2-amino-4-methylphenol [1]. The enzyme from the bacterium Comamonas testosteroni CNB-1 also has the activity of EC 1.13.11.76, 2-amino-5-chlorophenol 1,6-dioxygenase [2].
Cofactor Fe2+
History
Reactions 2-aminophenol + O(2) = 2-aminomuconate 6-semialdehyde.

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