| 英文名 |
2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase |
| Example Structure |
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| 别名 |
2-keto-3-deoxy-6-phosphogluconate aldolase, 2-keto-3-deoxygluconate aldolase, KD(P)G-aldolase, KDG aldolase, KDG-aldolase, KDGA, SacKdgA |
| EC Number |
4.1.2.55 |
| CAS编号 |
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| Comments |
In the archaeon?Sulfolobus solfataricus?the enzyme is involved in glucose and galactose catabolism via the branched variant of the Entner-Doudoroff pathway. It utilizes 2-dehydro-3-deoxy-6-phosphate-D-gluconate and 2-dehydro-3-deoxy-6-phosphate-D-galactonate with similar catalytic efficiency.?In vitro?the enzyme can also catalyse the cleavage of the non-phosphorylated forms 2-dehydro-3-deoxy-D-gluconate and 2-dehydro-3-deoxy-D-galactonate with much lower catalytic efficiency.?cf. EC?4.1.2.21, 2-dehydro-3-deoxy-6-phosphogalactonate aldolase, and EC?4.1.2.14, 2-dehydro-3-deoxy-phosphogluconate aldolase. |
| Cofactor |
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| History |
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| Reactions |
(1) 2-dehydro-3-deoxy-6-phospho-D-gluconate = pyruvate + D-glyceraldehyde 3-phosphate. (2) 2-dehydro-3-deoxy-6-phospho-D-galactonate = pyruvate + D-glyceraldehyde 3-phosphate. |
