| 英文名 |
2-deoxy-scyllo-inosose synthase |
| Example Structure |
 |
| 别名 |
AlloH, btrC, BtrC2, DOI synthase, DOIS, KanA, kanC, neoC, tbmA |
| EC Number |
4.2.3.124 |
| CAS编号 |
|
| Comments |
Requires Co2+?[2]. Involved in the biosynthetic pathways of several clinically important aminocyclitol antibiotics, including kanamycin, butirosin, neomycin and ribostamycin. Requires an NAD+?cofactor, which is transiently reduced during the reaction [1,4]. The enzyme from the bacterium?Bacillus circulans?forms a complex with the glutamine amidotransferase subunit of pyridoxal 5′-phosphate synthase (EC?4.3.3.6), which appears to stabilize the complex [6,7]. |
| Cofactor |
cobalt cation |
| History |
|
| Reactions |
D-glucose-6-phosphate = 2-deoxy-L-scyllo-inosose + phosphate. |
