| 英文名 |
2-hydroxy-7-methoxy-5-methyl-1-naphthoate-CoA ligase |
| Example Structure |
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| 别名 |
naphthoic acid/coenzyme A ligase, naphthoyl CoA ligase, NcsB2 |
| EC Number |
6.2.1.43 |
| CAS编号 |
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| Comments |
The enzyme from the bacterium?Streptomyces carzinostaticus?is involved in the attachment of the 2-hydroxy-7-methoxy-5-methyl-1-naphthoate moiety of the antibiotic neocarzinostatin.?In vitro?the enzyme also catalyses the activation of other 1-naphthoic acid analogues, e.g. 2-hydroxy-5-methyl-1-naphthoate or 2,7-dihydroxy-5-methyl-1-naphthoate. |
| Cofactor |
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| History |
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| Reactions |
Atp + 2-hydroxy-7-methoxy-5-methyl-1-naphthoate + CoA = amp + diphosphate + 2-hydroxy-7-methoxy-5-methyl-1-naphthoyl-CoA. |
