| 英文名 |
2-hydroxymuconate-6-semialdehyde dehydrogenase |
| Example Structure |
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| 别名 |
2-hydroxymuconate semialdehyde dehydrogenase, 2-hydroxymuconic semialdehyde dehydrogenase, 5C-2HMS dehydrogenase, HMS dehydrogenase, NAD+-dependent 2-hydroxy-muconic 6-semialdehyde dehydrogenase, NahI, praB, XylG |
| EC Number |
1.2.1.85 |
| CAS编号 |
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| Comments |
This substrate for this enzyme is formed by meta ring cleavage of catechol (EC 1.13.11.2, catechol 2,3-dioxygenase), and is an intermediate in the bacterial degradation of several aromatic compounds. Has lower activity with benzaldehyde [1]. Activity with NAD+ is more than 10-fold higher than with NADP+ [3]. cf. EC 1.2.1.32, aminomuconate-semialdehyde dehydrogenase. |
| Cofactor |
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| History |
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| Reactions |
2-hydroxymuconate-6-semialdehyde + NAD(+) + H(2)O = (2Z,4E)-2- hydroxyhexa-2,4-dienedioate + Nadh. |
