2-iminoacetate synthase EC#: 4.1.99.19; 凯望编码 (ChemWhat Code): 1382217
| 英文名 | 2-iminoacetate synthase |
| Example Structure |  |
| 别名 | thiH |
| EC Number | 4.1.99.19 |
| CAS编号 | |
| Comments | Binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable?S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the?S-adenosyl-L-methionine to produce methionine and a 5-deoxyadenosin-5-yl radical that is crucial for the conversion of the substrate. Part of the pathway for thiamine biosynthesis. Formerly EC?1.3.99.n2. |
| Cofactor | iron-sulfur |
| History | |
| Reactions | L-tyrosine + S-adenosyl-L-methionine + Nadph = 2-iminoacetate + 4-methylphenol + 5′-deoxyadenosine + L-methionine + NADP(+) + H(+). |
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