2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) EC#: 4.2.1.117; 凯望编码 (ChemWhat Code): 1382417

英文名 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming)
Example Structure Example Structure of 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) EC#: 4.2.1.117
别名 AcnD, SO_0343
EC Number 4.2.1.117
CAS编号
Comments Catalyses the dehydration of (2S,3S)-2-methylcitrate, forming the?trans?isomer of 2-methyl-aconitate (unlike EC?4.2.1.79, which forms only the?cis?isomer). Part of a propionate degradation pathway. The enzyme from?Shewanella oneidensis?can also accept citrate and?cis-aconitate, but activity with (2S,3S)-2-methylcitrate was approximately 2.5-fold higher. 2-methylisocitrate and isocitrate were not substrates [1]. An iron-sulfur protein.
Cofactor iron-sulfur
History
Reactions (2S,3S)-2-methylcitrate = 2-methyl-trans-aconitate + H(2)O.

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