2-oxo-acid reductase EC#: 1.1.99.30; 凯望编码 (ChemWhat Code): 1373706
| 英文名 | 2-oxo-acid reductase |
| Example Structure |  |
| 别名 | (2R)-hydroxycarboxlate viologen oxidoreductase, (2R)-hydroxycarboxlate-viologen-oxidoreductase, (2R)-hydroxycarboxylate-viologen-oxidoreductase, 2-oxoacid reductase, D-2-hydroxy acid dehydrogenase, dehydrogenase, D-2-hydroxy acid, HVOR, hydroxy carboxylate viologen oxidoreductase, hydroxycarboxlate-oxidoreductase, hydroxycarboxlate-viologen-oxidoreductase |
| EC Number | 1.1.99.30 |
| CAS编号 | |
| Comments | Contains [4Fe-4S] and a mononucleotide molybdenum (pyranopterin) cofactor. Has broad substrate specificity, with 2-oxo-monocarboxylates and 2-oxo-dicarboxylates acting as substrates. Branching in a substrate at the C-3 position results in loss of activity. The enzyme from Proteus sp. is inactivated by oxygen. |
| Cofactor | iron-sulfur;Mo-molybdopterin |
| History | |
| Reactions | A (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor. |
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