2-oxoglutarate reductase EC#: 1.1.1.399; 凯望编码 (ChemWhat Code): 1373530

英文名 2-oxoglutarate reductase
Example Structure Example Structure of 2-oxoglutarate reductase EC#: 1.1.1.399
别名
EC Number 1.1.1.399
CAS编号
Comments The enzyme catalyses a reversible reaction. The enzyme from the bacterium Peptoniphilus asaccharolyticus is specific for (R)-2-hydroxyglutarate [1,2]. The SerA enzyme from Escherichia coli can also accept (S)-2-hydroxyglutarate with a much higher Km, and also catalyses the activity of EC 1.1.1.95, phosphoglycerate dehydrogenase [3].
Cofactor
History
Reactions (R)-2-hydroxyglutarate + NAD(+) = 2-oxoglutarate + Nadh.

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