| 英文名 |
2-oxopent-4-enoate hydratase |
| Example Structure |
 |
| 别名 |
2-hydroxypent-2,4-dienoate hydratase, 2-hydroxypenta-2,4-dienoate hydratase, 2-hydroxypentadienoic acid hydratase, 2-keto-4-pentenoate hydratase, 2-keto-4-pentenoate(vinylpyruvate)hydratase, 2-keto-4-pentenoic acid hydratase, BphH, HPD hydratase, MhpD, OEH 2-keto-4-pentenoate hydratase, vinylpyruvate hydratase |
| EC Number |
4.2.1.80 |
| CAS编号 |
227181-25-1;229017-66-7;64427-80-1 |
| Comments |
The enzyme is involved in the catechol?meta-cleavage pathway, a major mechanism for degradation of aromatic compounds. Also acts, more slowly, on?cis-2-oxohex-4-enoate, but not on the?trans-isomer. The enzyme was named when it was thought that the substrate is 2-oxopent-4-enoate. However, it was later found that the actual substrate is its tautomer (2Z)-2-hydroxypenta-2,4-dienoate. In some organisms the enzyme forms a complex with EC?4.1.1.77, 2-oxo-3-hexenedioate decarboxylase (previously named 4-oxalocrotonate decarboxylase). |
| Cofactor |
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| History |
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| Reactions |
4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H(2)O. |