| 英文名 |
2-(S)-hydroxypropyl-CoM dehydrogenase |
| Example Structure |
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| 别名 |
(S)-hydroxypropyl-coenzyme M dehydrogenase, (S)-hydroxypropylthioethanesulfonate dehydrogenase, 2-(2-(S)-hydroxypropylthio)ethanesulfonate dehydrogenase, HPCDH3, S-HPCDH, xecE1, xecE3 |
| EC Number |
1.1.1.269 |
| CAS编号 |
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| Comments |
The enzyme is highly specific for (S)-2-hydroxyalkyl thioethers of CoM, in contrast to EC 1.1.1.268, 2-(R)-hydroxypropyl-CoM dehydrogenase, which is highly specific for the (R)-enantiomer. This enzyme forms component IV of a four-component enzyme system {comprising EC 4.4.1.23 (2-hydroxypropyl-CoM lyase; component I), EC 1.8.1.5 [2-oxopropyl-CoM reductase (carboxylating); component II], EC 1.1.1.268 [2-(R)-hydroxypropyl-CoM dehydrogenase; component III] and EC 1.1.1.269 [2-(S)-hydroxypropyl-CoM dehydrogenase; component IV]} that is involved in epoxyalkane carboxylation in Xanthobacter sp. strain Py2. |
| Cofactor |
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| History |
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| Reactions |
2-(S)-hydroxypropyl-CoM + NAD(+) = 2-oxopropyl-CoM + Nadh. |
