| 英文名 |
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase |
| Example Structure |
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| 别名 |
(1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase, MenH, SHCHC, SHCHC synthase, YfbB |
| EC Number |
4.2.99.20 |
| CAS编号 |
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| Comments |
This enzyme is involved in the biosynthesis of vitamin K2 (menaquinone). In most anaerobes and all Gram-positive aerobes, menaquinone is the sole electron transporter in the respiratory chain and is essential for their survival. It had previously been thought that the reactions carried out by this enzyme and EC?2.2.1.9, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase, were carried out by a single enzyme but this has since been disproved [2]. |
| Cofactor |
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| History |
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| Reactions |
5-enolpyruvoyl-6-hydroxy-2-succinylcyclohex-3-ene-1-carboxylate = (1R,6R)-6-hydroxy-2-succinylcyclohexa-2,4-diene-1-carboxylate + pyruvate. |
