| 英文名 |
23S rRNA (guanine2069-N7)-methyltransferase |
| Example Structure |
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| 别名 |
3S rRNA m7G2069 methyltransferase, bifunctional methyltransferase, m2G2069 methyltransferase, ribosomal large subunit methyltransferase, rlmK, RlmKL, SAV1081, Smu472, ycbY |
| EC Number |
2.1.1.264 |
| CAS编号 |
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| Comments |
The enzyme specifically methylates guanine2069 at position N7 in 23S rRNA. In ¦Ã-proteobacteria the enzyme also catalyses EC 2.1.1.173, 23S rRNA (guanine2445-N2)-methyltransferase, while in ¦Â-proteobacteria the activities are carried out by separate proteins [1]. The enzyme from the ¦Ã-proteobacterium Escherichia coli has RNA unwinding activity as well [1]. |
| Cofactor |
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| History |
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| Reactions |
S-adenosyl-L-methionine + guanine(2069) in 23S rRNA = S-adenosyl-L- homocysteine + N(7)-methylguanine(2069) in 23S rRNA. |
