| 英文名 |
2,4-dinitrotoluene dioxygenase |
| Example Structure |
 |
| 别名 |
2,4-dinitrotoluene dioxygenase, 2,4-DNT dioxygenase, 2,4-DNTDO, DDO, DNT dioxygenase, dntA, DntAc, DNTDO |
| EC Number |
1.14.12.24 |
| CAS编号 |
|
| Comments |
This enzyme, characterized from the bacterium Burkholderia sp. strain DNT, is a member of the naphthalene family of bacterial Rieske non-heme iron dioxygenases. It comprises a multicomponent system, containing a Rieske [2Fe-2S] ferredoxin, an NADH-dependent flavoprotein reductase (EC 1.18.1.3 ferredoxin¡ªNAD+ reductase), and an ¦Á3¦Â3 oxygenase. The enzyme forms a cis-dihydroxylated product that spontaneously rearranges to form a catechol with accompanying release of nitrite. It does not act on nitrobenzene. cf. EC 1.14.12.23 nitroarene dioxygenase. |
| Cofactor |
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| History |
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| Reactions |
2,4-dinitrotoluene + Nadh + O(2) = 4-methyl-5-nitrocatechol + nitrite + NAD(+). |
