| 英文名 |
3-dehydroquinate synthase II |
| Example Structure |
 |
| 别名 |
aroB’, aroB2, dehydroquinate synthase II, DHQ synthase, DHQ synthase II, DHQS, MJ1249, MJ1249 protein, type II 3-dehydroquinate synthase |
| EC Number |
1.4.1.24 |
| CAS编号 |
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| Comments |
The enzyme, which was isolated from the archaeon Methanocaldococcus jannaschii, plays a key role in an alternative pathway for the biosynthesis of 3-dehydroquinate (DHQ), an intermediate of the canonical pathway for the biosynthesis of aromatic amino acids. The enzyme catalyses a two-step reaction – an oxidative deamination, followed by cyclization. |
| Cofactor |
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| History |
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| Reactions |
2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate + H(2)O + NAD(+) = 3-dehydroquinate + NH(3) + Nadh. |
