3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase EC#: 2.5.1.132; 凯望编码 (ChemWhat Code): 1378077

英文名 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase
Example Structure Example Structure of 3-deoxy-D-glycero-D-galacto-nonulopyranosonate 9-phosphate synthase EC#: 2.5.1.132
别名 2-keto-3-deoxy-D-glycero-D-galacto-9-phosphonononic acid synthase, 2-keto-3-deoxy-D-glycero-D-galacto-nonulosonic acid 9-phosphate synthase, 3-deoxy-D-glycero-D-galacto-nononate 9-phosphate synthase, BT1714, KDN 9-phosphate synthase, KDN-9-P synthase, KDN-9-phosphate synthetase, KDN-9P synthase, N-acetylneuraminic acid phosphate synthase, Neu5Ac 9-phosphate synthase, neu5ac-9-P synthase, NeuNAc-9-P synthase
EC Number 2.5.1.132
CAS编号
Comments The enzyme participates in the biosynthesis of the sialic acid 3-deoxy-D-glycero-D-galacto-nononate (KDN). The human sialic acid synthase (EC 2.5.1.57) is also able to catalyse the reaction. KDN is abundant in extracellular glycoconjugates of lower vertebrates such as fish and amphibians, but is also found in the capsular polysaccharides of bacteria that belong to the Bacteroides genus.
Cofactor
History
Reactions Phosphoenolpyruvate + D-mannose 6-phosphate + H(2)O = 3-deoxy-D-glycero- D-galacto-nononate 9-phosphate + phosphate.

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