| 英文名 |
3-hydroxypropionate dehydrogenase (NADP+) |
| Example Structure |
 |
| 别名 |
3-HIBADH, 3-hydroxyisobutyrate dehydrogenase, 3-hydroxypropionate dehydrogenase, malonate semialdehyde reductase (NADPH), malonic semialdehyde reductase, malonyl-CoA reductase, Msed_1993 |
| EC Number |
1.1.1.298 |
| CAS编号 |
|
| Comments |
Catalyses the reduction of malonate semialdehyde to 3-hydroxypropanoate, a key step in the 3-hydroxypropanoate and the 3-hydroxypropanoate/4-hydroxybutyrate cycles, autotrophic CO2 fixation pathways found in some green non-sulfur phototrophic bacteria and archaea, respectively [1,2]. The enzyme from Chloroflexus aurantiacus is bifunctional, and also catalyses the upstream reaction in the pathway, EC 1.2.1.75 [3]. Different from EC 1.1.1.59 [3-hydroxypropionate dehydrogenase (NAD+)] by cofactor preference. |
| Cofactor |
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| History |
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| Reactions |
3-hydroxypropanoate + NADP(+) = 3-oxopropanoate + Nadph. |
