3alpha-hydroxysteroid 3-dehydrogenase EC#: 1.1.1.357; 凯望编码 (ChemWhat Code): 1373476

英文名 3alpha-hydroxysteroid 3-dehydrogenase
Example Structure Example Structure of 3alpha-hydroxysteroid 3-dehydrogenase EC#: 1.1.1.357
别名
EC Number 1.1.1.357
CAS编号
Comments The enzyme acts on multiple 3¦Á-hydroxysteroids, such as androsterone and 5 ¦Á-dihydrotestosterone. The mammalian enzymes are involved in inactivation of steroid hormones, while the bacterial enzymes are involved in steroid degradation. This entry stands for enzymes whose stereo-specificity with respect to NAD+ or NADP+ is not known. [cf. EC 1.1.1.50, 3¦Á-hydroxysteroid 3-dehydrogenase (Si-specific) and EC 1.1.1.213, 3¦Á-hydroxysteroid 3-dehydrogenase (Re-specific)].
Cofactor
History
Reactions A 3-alpha-hydroxysteroid + NAD(P)(+) = a 3-oxosteroid + NAD(P)H.

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