| 英文名 |
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase |
| Example Structure |
 |
| 别名 |
46 kDa hydratase, 46 kDa hydratase 2, perMFE-2 |
| EC Number |
4.2.1.107 |
| CAS编号 |
|
| Comments |
This enzyme forms part of the rat peroxisomal multifunctional enzyme perMFE-2, which also exhibits a dehydrogenase activity. The enzyme is involved in the ¦Â-oxidation of the cholesterol side chain in the cholic-acid-biosynthesis pathway. |
| Cofactor |
|
| History |
|
| Reactions |
(24R,25R)-3-alpha,7-alpha,12-alpha,24-tetrahydroxy-5-beta-cholestanoyl- CoA = (24E)-3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl- CoA + H(2)O. |