3beta-hydroxycholanate 3-dehydrogenase (NADP+) EC#: 1.1.1.393; 凯望编码 (ChemWhat Code): 1373523

英文名 3beta-hydroxycholanate 3-dehydrogenase (NADP+)
Example Structure Example Structure of 3beta-hydroxycholanate 3-dehydrogenase (NADP+) EC#: 1.1.1.393
别名
EC Number 1.1.1.393
CAS编号
Comments This bacterial enzyme is involved, along with EC 1.1.1.52, 3¦Á-hydroxycholanate dehydrogenase (NAD+), or EC 1.1.1.392, 3¦Á-hydroxycholanate dehydrogenase (NADP+), in the modification of secondary bile acids to form 3¦Â-bile acids (also known as iso-bile acids). The enzyme catalyses the reaction in the reduction direction in vivo. Also acts on related 3-oxo bile acids. cf. EC 1.1.1.391, 3¦Â-hydroxycholanate 3-dehydrogenase (NAD+).
Cofactor
History
Reactions Isolithocholate + NADP(+) = 3-oxo-5-beta-cholan-24-oate + Nadph.

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