| 英文名 |
4-hydroxybutanoyl-CoA dehydratase |
| Example Structure |
 |
| 别名 |
4-hydroxybutyryl-CoA dehydratase, 4-hydroxybutyryl-coenzyme A dehydratase, 4HBD, AbfD, Igni_0595, Msed_1321, Tneu_0422 |
| EC Number |
4.2.1.120 |
| CAS编号 |
|
| Comments |
Contains FAD and a [4Fe-4S] iron-sulfur cluster. The enzyme has been characterized from several microorganisms, including?Clostridium kluyveri, where it participates in succinate fermentation [1,2],?Clostridium aminobutyricum, where it participates in 4-aminobutyrate degradation [3,4], and?Metallosphaera sedula, where it participates in the 3-hydroxypropionate/4-hydroxybutyrate cycle, an autotrophic CO2?fixation pathway found in some thermoacidophilic archaea [5]. |
| Cofactor |
iron-sulfur
FAD |
| History |
|
| Reactions |
4-hydroxybutanoyl-CoA = (E)-but-2-enoyl-CoA + H(2)O. |