5-hydroxybenzimidazole synthase EC#: 4.1.99.23; 凯望编码 (ChemWhat Code): 1382222
| 英文名 | 5-hydroxybenzimidazole synthase |
| Example Structure |  |
| 别名 | bzaF, HBI synthase |
| EC Number | 4.1.99.23 |
| CAS编号 | |
| Comments | The enzyme, purified from bacteria, is part of the anaerobic pathway for cobalamin biosynthesis. It binds a [4Fe-4S] cluster that is coordinated by 3 cysteines and an exchangeable?S-adenosyl-L-methionine molecule. The first stage of catalysis is reduction of the?S-adenosyl-L-methionine to produce?L-methionine and a 5′-deoxyadenosin-5′-yl radical that is crucial for the conversion of the substrate. |
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