| 英文名 |
5′-(N7-methyl 5′-triphosphoguanosine)-[mRNA] diphosphatase |
| Example Structure |
![Example Structure of 5'-(N7-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase EC#: 3.6.1.59](/wp-content/uploads/enzyme-structure/3.6.1.59.jpg) |
| 别名 |
Dcps, Dcs1, m7GpppN m7GMP phosphohydrolase, m7GpppX pyrophosphatase, yDcps, YLR270W |
| EC Number |
3.6.1.59 |
| CAS编号 |
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| Comments |
The enzyme removes (decaps) the?N7-methylguanosine 5-phosphate cap from an mRNA degraded to a maximal length of 10 nucleotides [3,6]. Decapping is an important process in the control of eukaryotic mRNA degradation. The enzyme functions to clear the cell of cap structure following decay of the RNA body [2]. The nematode enzyme can also decap triply methylated substrates, 5′-(N2,N2,N7-trimethyl 5′-triphosphoguanosine)-[mRNA] [4]. |
| Cofactor |
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| History |
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| Reactions |
A 5′-(N(7)-methyl 5′-triphosphoguanosine)-[mRNA] + H(2)O = N(7)- methylguanosine 5′-phosphate + a 5′-diphospho-[mRNA]. |
