| 英文名 |
(5R)-carbapenem-3-carboxylate synthase |
| Example Structure |
 |
| 别名 |
carbapenem synthase, CarC |
| EC Number |
1.14.20.3 |
| CAS编号 |
|
| Comments |
Requires Fe2+. The enzyme is involved in the biosynthesis of the carbapenem ¦Â-lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium Pectobacterium carotovorum. It catalyses a stereoinversion at C5 and introduces a double bond between C-2 and C-3. |
| Cofactor |
Fe2+ |
| History |
|
| Reactions |
(3S,5S)-carbapenam-3-carboxylate + 2-oxoglutarate + O(2) = (5R)-carbapen- 2-em-3-carboxylate + succinate + CO(2) + H(2)O. |
